Using data from a genome-wide association study of 907 individuals with childhood acute lymphoblastic leukemia (cases) and 2,398 controls and with validation in samples totaling 2,386 cases and 2,419 controls, we have shown that common variation at 9p21.3 (rs3731217, intron 1 of CDKN2A) influences acute lymphoblastic leukemia risk (odds ratio = 0.71, P = 3.01 x 10(-11)), irrespective of cell lineage
There is increasing evidence from genome-wide association studies for a strong inherited genetic bas...
The locus CDKN2A/B (9p21.3), which comprises the tumor suppressors genes CDKN2A and CDKN2B and the l...
International audienceRecent genome-wide association studies (GWAS) focusing on pediatric acute lymp...
Using data from a genome-wide association study of 907 individuals with childhood acute lymphoblasti...
Genome-wide association studies (GWAS) have provided strong evidence for inherited predisposition to...
There is increasing evidence from genome-wide association studies for a strong inherited genetic bas...
Paediatric B-cell precursor acute lymphoblastic leukaemia (BCP-ALL) is the most common cancer of chi...
The locus CDKN2A/B (9p21.3), which comprises the tumor suppressors genes CDKN2A and CDKN2B and the l...
Paediatric B-cell precursor acute lymphoblastic leukaemia (BCP-ALL) is the most common cancer of chi...
Paediatric B-cell precursor acute lymphoblastic leukaemia (BCP-ALL) is the most common cancer of chi...
Genome-wide association studies (GWAS) have provided strong evidence for inherited predisposition to...
The locus CDKN2A/B (9p21.3), which comprises the tumor suppressors genes CDKN2A and CDKN2B and the l...
Genome-wide association studies (GWASs) have shown that common genetic variation contributes to the ...
Acute lymphoblastic leukemia (ALL) is the major pediatric cancer diagnosed in economically developed...
To identify risk variants for childhood acute lymphoblastic leukemia (ALL), we conducted a genome-wi...
There is increasing evidence from genome-wide association studies for a strong inherited genetic bas...
The locus CDKN2A/B (9p21.3), which comprises the tumor suppressors genes CDKN2A and CDKN2B and the l...
International audienceRecent genome-wide association studies (GWAS) focusing on pediatric acute lymp...
Using data from a genome-wide association study of 907 individuals with childhood acute lymphoblasti...
Genome-wide association studies (GWAS) have provided strong evidence for inherited predisposition to...
There is increasing evidence from genome-wide association studies for a strong inherited genetic bas...
Paediatric B-cell precursor acute lymphoblastic leukaemia (BCP-ALL) is the most common cancer of chi...
The locus CDKN2A/B (9p21.3), which comprises the tumor suppressors genes CDKN2A and CDKN2B and the l...
Paediatric B-cell precursor acute lymphoblastic leukaemia (BCP-ALL) is the most common cancer of chi...
Paediatric B-cell precursor acute lymphoblastic leukaemia (BCP-ALL) is the most common cancer of chi...
Genome-wide association studies (GWAS) have provided strong evidence for inherited predisposition to...
The locus CDKN2A/B (9p21.3), which comprises the tumor suppressors genes CDKN2A and CDKN2B and the l...
Genome-wide association studies (GWASs) have shown that common genetic variation contributes to the ...
Acute lymphoblastic leukemia (ALL) is the major pediatric cancer diagnosed in economically developed...
To identify risk variants for childhood acute lymphoblastic leukemia (ALL), we conducted a genome-wi...
There is increasing evidence from genome-wide association studies for a strong inherited genetic bas...
The locus CDKN2A/B (9p21.3), which comprises the tumor suppressors genes CDKN2A and CDKN2B and the l...
International audienceRecent genome-wide association studies (GWAS) focusing on pediatric acute lymp...