Add to ORKGThe syntheses of four D-myo-inositol 1,4,5-trisphosphate (InsP(3)) derivatives, incorporating phosphate bioisosteres at the 5-position, are reported. The methyl phosphate ester and sulfate derivatives retain InsP(3) receptor (InsP(3)R) agonist activity; the compounds that possess a methylphosphonate or a carboxymethyl moiety are InsP(3)R antagonists
Racemic myo-inositol-1,4,5-trisphosphate and myo-inositol-1,4-bisphosphate, which are respectively a...
The synthesis of d-myo-inositol 1,4,5-trisphosphate (InsP3) from methyl α-d-glucopyranose, via a typ...
The intracellular second messenger InsP₃ is a vital molecule in the regulation of Ca²⁺ signalling. C...
The syntheses of four D-myo-inositol 1,4,5-trisphosphate (InsP(3)) derivatives, incorporating phosph...
The syntheses of four D-myo-inositol 1,4,5-trisphosphate (InsP(3)) derivatives, incorporating phosph...
The syntheses of four d-myo-inositol 1,4,5-trisphosphate (InsP3) derivatives, incorporating phosphat...
The design of a range of 4-position-modified D-myo-inositol 1,4,5-trisphosphate derivatives is descr...
The design of a range of 4-position-modified D-myo-inositol 1,4,5-trisphosphate derivatives is descr...
Well-regulated Ca2+ signalling is essential for every living organism, and disruption of this signal...
In order to enable the study of the intracellular second messenger D-myo-inositol 1,4,5-trisphosphat...
The intracellular second messenger InsP₃ is a vital molecule in the regulation of Ca²⁺ signalling. C...
Inositol 1,4,5-trisphosphate receptors (IP3Rs) are intracellular Ca(2+) channels that are widely exp...
The synthesis of D-myo-inositol 1,4,5-trisphosphate (InsP(3)) from methyl alpha-D-glucopyranose, via...
Analogues of the Ca2+-releasing intracellular messenger D-myo-inositol 1,4,5-trisphosphate [1, Ins(1...
A number of myo-inositol phosphates (IPn) have been implicated as either second messengers or key me...
Racemic myo-inositol-1,4,5-trisphosphate and myo-inositol-1,4-bisphosphate, which are respectively a...
The synthesis of d-myo-inositol 1,4,5-trisphosphate (InsP3) from methyl α-d-glucopyranose, via a typ...
The intracellular second messenger InsP₃ is a vital molecule in the regulation of Ca²⁺ signalling. C...
The syntheses of four D-myo-inositol 1,4,5-trisphosphate (InsP(3)) derivatives, incorporating phosph...
The syntheses of four D-myo-inositol 1,4,5-trisphosphate (InsP(3)) derivatives, incorporating phosph...
The syntheses of four d-myo-inositol 1,4,5-trisphosphate (InsP3) derivatives, incorporating phosphat...
The design of a range of 4-position-modified D-myo-inositol 1,4,5-trisphosphate derivatives is descr...
The design of a range of 4-position-modified D-myo-inositol 1,4,5-trisphosphate derivatives is descr...
Well-regulated Ca2+ signalling is essential for every living organism, and disruption of this signal...
In order to enable the study of the intracellular second messenger D-myo-inositol 1,4,5-trisphosphat...
The intracellular second messenger InsP₃ is a vital molecule in the regulation of Ca²⁺ signalling. C...
Inositol 1,4,5-trisphosphate receptors (IP3Rs) are intracellular Ca(2+) channels that are widely exp...
The synthesis of D-myo-inositol 1,4,5-trisphosphate (InsP(3)) from methyl alpha-D-glucopyranose, via...
Analogues of the Ca2+-releasing intracellular messenger D-myo-inositol 1,4,5-trisphosphate [1, Ins(1...
A number of myo-inositol phosphates (IPn) have been implicated as either second messengers or key me...
Racemic myo-inositol-1,4,5-trisphosphate and myo-inositol-1,4-bisphosphate, which are respectively a...
The synthesis of d-myo-inositol 1,4,5-trisphosphate (InsP3) from methyl α-d-glucopyranose, via a typ...
The intracellular second messenger InsP₃ is a vital molecule in the regulation of Ca²⁺ signalling. C...