A direct and versatile route for the reliable synthesis of trans-2,5-disubstituted pyrrolidines from pyroglutamic acid is reported, which can be conducted at scale and without chromatographic purification of key intermediates
A facile solid phase synthesis of 2,4,6,7-tetrasubstituted pyrrolo[2,3-d]pyrimidines is described. T...
The partial reduction of N-Boc pyrroles has been explored giving stereoselective routes to disubstit...
A new synthetic route to (2S,5S)-dimethylpyrrolidine 1, which can also be applied to the synthesis o...
A direct and versatile route for the reliable synthesis of trans-2,5-disubstituted pyrrolidines from...
A concise approach to cis-2,5-disubstituted pyrrolidines is reported, which relies upon N-tert-butox...
A direct and versatile route enabling the regio- and diastereoselective synthesis of 2,5-disubstitut...
Methodology for the diastereoselective synthesis of 2,5-disubstituted pyrrolidines by reduction of e...
to constitute major frameworks of alkaloids, which display diverse and potent biological activities....
The (+/-)-cis-5-arylcarbamoyl-2-ethoxycarbonylpyrrolidines 6a-g were firstly synthesized in 53-64% y...
Palladium(II)-catalyzed aerobic oxidative cyclization of alkenes with tethered <i>tert</i>-butanesul...
Wittig reaction of 4-[(4-methylphenyl)sulfonyl]-1-(triphenylphosphoranylidene)butan-2-one with N-pro...
[reaction: see text] The partial reduction of electron-deficient 2,5-disubstituted pyrroles has been...
Enantiopure <i>trans</i>-2,5-disubstituted trifluoromethylpyrrolidines were prepared on a several gr...
Design and synthesis of ligands based on trans-2,5-disubstitutedpyrrolidines and their application i...
Pyrrolidines are widely prevalent in pharmaceuticals, catalysis and agrochemicals. The (3+2) cycload...
A facile solid phase synthesis of 2,4,6,7-tetrasubstituted pyrrolo[2,3-d]pyrimidines is described. T...
The partial reduction of N-Boc pyrroles has been explored giving stereoselective routes to disubstit...
A new synthetic route to (2S,5S)-dimethylpyrrolidine 1, which can also be applied to the synthesis o...
A direct and versatile route for the reliable synthesis of trans-2,5-disubstituted pyrrolidines from...
A concise approach to cis-2,5-disubstituted pyrrolidines is reported, which relies upon N-tert-butox...
A direct and versatile route enabling the regio- and diastereoselective synthesis of 2,5-disubstitut...
Methodology for the diastereoselective synthesis of 2,5-disubstituted pyrrolidines by reduction of e...
to constitute major frameworks of alkaloids, which display diverse and potent biological activities....
The (+/-)-cis-5-arylcarbamoyl-2-ethoxycarbonylpyrrolidines 6a-g were firstly synthesized in 53-64% y...
Palladium(II)-catalyzed aerobic oxidative cyclization of alkenes with tethered <i>tert</i>-butanesul...
Wittig reaction of 4-[(4-methylphenyl)sulfonyl]-1-(triphenylphosphoranylidene)butan-2-one with N-pro...
[reaction: see text] The partial reduction of electron-deficient 2,5-disubstituted pyrroles has been...
Enantiopure <i>trans</i>-2,5-disubstituted trifluoromethylpyrrolidines were prepared on a several gr...
Design and synthesis of ligands based on trans-2,5-disubstitutedpyrrolidines and their application i...
Pyrrolidines are widely prevalent in pharmaceuticals, catalysis and agrochemicals. The (3+2) cycload...
A facile solid phase synthesis of 2,4,6,7-tetrasubstituted pyrrolo[2,3-d]pyrimidines is described. T...
The partial reduction of N-Boc pyrroles has been explored giving stereoselective routes to disubstit...
A new synthetic route to (2S,5S)-dimethylpyrrolidine 1, which can also be applied to the synthesis o...