Add to ORKGA Michael addition/iminium ion cyclization cascade of enones with tryptamine-derived ureas under BINOL phosphoric acid (BPA) catalysis is reported. The cascade reaction tolerates a wide variety of easily synthesized tryptamine-derived ureas, including those bearing substituents on the distal nitrogen atom of the urea moiety, affording polyheterocyclic products in good yields and good to excellent enantioselectivities
An unprecedented intermolecular iminium/enamine Michael addition on enals has been developed by taki...
An unprecedented organocatalytic asymmetric Michael/cyclization cascade reaction of 3-isothiocyanato...
A challenging asymmetric reaction (aza-Michael addition of imides to enones) has been optimized thro...
A Michael addition/iminium ion cyclization cascade of enones with tryptamine-derived ureas under BIN...
Enantioselective construction of pyrroloindolines <i>via</i> chiral phosphoric acid catalyzed cascad...
This thesis concerns the development of the first BINOL phosphoric acid (BPA) catalysed enantioselec...
A direct enantio- and diastereoselective N-acyliminium cyclization cascade through chiral phosphoric...
Chapter 1 introduces the strategies to prepare enantioenriched compounds, specifically focusing on t...
An efficient aminocatalytic enantioselective double-activation strategy has been developed that comb...
Allenamides represent a versatile building block but has not been widely explored in asymmetric orga...
Products of a novel iminium-catalyzed oxa-Michael addition undergo a kinetic resolution by a subsequ...
The use of isothioureas as Lewis base organocatalysts has been widely studied by the Smith group and...
The combined use of rhodium and cinchona-based squaramide has first been introduced for asymmetric r...
The ability to control absolute stereochemistry is a powerful tool in organic synthesis. Given the u...
Pyrroloindoline and bispyrroloindoline are a subclass of alkaloid structural motifs that commonly ex...
An unprecedented intermolecular iminium/enamine Michael addition on enals has been developed by taki...
An unprecedented organocatalytic asymmetric Michael/cyclization cascade reaction of 3-isothiocyanato...
A challenging asymmetric reaction (aza-Michael addition of imides to enones) has been optimized thro...
A Michael addition/iminium ion cyclization cascade of enones with tryptamine-derived ureas under BIN...
Enantioselective construction of pyrroloindolines <i>via</i> chiral phosphoric acid catalyzed cascad...
This thesis concerns the development of the first BINOL phosphoric acid (BPA) catalysed enantioselec...
A direct enantio- and diastereoselective N-acyliminium cyclization cascade through chiral phosphoric...
Chapter 1 introduces the strategies to prepare enantioenriched compounds, specifically focusing on t...
An efficient aminocatalytic enantioselective double-activation strategy has been developed that comb...
Allenamides represent a versatile building block but has not been widely explored in asymmetric orga...
Products of a novel iminium-catalyzed oxa-Michael addition undergo a kinetic resolution by a subsequ...
The use of isothioureas as Lewis base organocatalysts has been widely studied by the Smith group and...
The combined use of rhodium and cinchona-based squaramide has first been introduced for asymmetric r...
The ability to control absolute stereochemistry is a powerful tool in organic synthesis. Given the u...
Pyrroloindoline and bispyrroloindoline are a subclass of alkaloid structural motifs that commonly ex...
An unprecedented intermolecular iminium/enamine Michael addition on enals has been developed by taki...
An unprecedented organocatalytic asymmetric Michael/cyclization cascade reaction of 3-isothiocyanato...
A challenging asymmetric reaction (aza-Michael addition of imides to enones) has been optimized thro...