The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) that consists of highly conserved heptapeptide repeats with the consensus sequence Tyr-Ser-Pro-Thr-Ser-Pro-Ser. Yeast cells with a partially truncated CTD grow slowly, are temperature- and cold-sensitive, and are unable to fully activate transcription of some genes. Screening a yeast wild-type cDNA library by means of comparative hybridization we find that CTD truncation preferentially reduces transcription of genes encoding glycolytic enzymes. Using a newly developed dual reporter assay we demonstrate that sensitivity to CTD truncation is conferred by the glycolytic gene promoters. Expression driven by glycolytic gene promoters is reduced, on aver...
Eukaryotic RNA polymerase II (Pol II) contains a tail-like, intrinsically disordered carboxy-termina...
In different phases of the transcription cycle, RNA polymerase (Pol) II recruits various factors via...
In different phases of the transcription cycle, RNA polymerase (Pol) II recruits various factors via...
Yeast cells lacking transcription elongation factor genes such as PPR2 (TFIIS) and ELP (Elongator) a...
Abstract Background The largest sub-unit of RNA polymerase II, Rpb1p, has long been known to be subj...
Phosphorylation of the RNA polymerase (Pol) II C-terminal domain (CTD) repeats (1-YSPTSPS-7) is coup...
AbstractThe carboxy-terminal domain of the large subunit of mouse and human RNA polymerase II contai...
The C-terminal domain (CTD) of the largest subunit in DNA-dependent RNA polymerase II (RNAP II) is e...
The C-terminal domain (CTD) of the largest subunit in DNA-dependent RNA polymerase II (RNAP II) is e...
Transcription is the process by which information encoded in the DNA is read by the cell. RNAPII is ...
The carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II plays an important ro...
The RNA polymerase II carboxyl-terminal domain (CTD) consists of tandem repeats of consensus sequenc...
grantor: University of TorontoThe form of RNA polymerase II (RNAPII) that binds preferenti...
The cloning of the largest subunit of RNA polymerase II (pol II) from mouse and Saccharomyces cerevi...
The carboxy-terminal domain (CTD) of RNA polymerase (Pol) II is an intrinsically disordered low-comp...
Eukaryotic RNA polymerase II (Pol II) contains a tail-like, intrinsically disordered carboxy-termina...
In different phases of the transcription cycle, RNA polymerase (Pol) II recruits various factors via...
In different phases of the transcription cycle, RNA polymerase (Pol) II recruits various factors via...
Yeast cells lacking transcription elongation factor genes such as PPR2 (TFIIS) and ELP (Elongator) a...
Abstract Background The largest sub-unit of RNA polymerase II, Rpb1p, has long been known to be subj...
Phosphorylation of the RNA polymerase (Pol) II C-terminal domain (CTD) repeats (1-YSPTSPS-7) is coup...
AbstractThe carboxy-terminal domain of the large subunit of mouse and human RNA polymerase II contai...
The C-terminal domain (CTD) of the largest subunit in DNA-dependent RNA polymerase II (RNAP II) is e...
The C-terminal domain (CTD) of the largest subunit in DNA-dependent RNA polymerase II (RNAP II) is e...
Transcription is the process by which information encoded in the DNA is read by the cell. RNAPII is ...
The carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II plays an important ro...
The RNA polymerase II carboxyl-terminal domain (CTD) consists of tandem repeats of consensus sequenc...
grantor: University of TorontoThe form of RNA polymerase II (RNAPII) that binds preferenti...
The cloning of the largest subunit of RNA polymerase II (pol II) from mouse and Saccharomyces cerevi...
The carboxy-terminal domain (CTD) of RNA polymerase (Pol) II is an intrinsically disordered low-comp...
Eukaryotic RNA polymerase II (Pol II) contains a tail-like, intrinsically disordered carboxy-termina...
In different phases of the transcription cycle, RNA polymerase (Pol) II recruits various factors via...
In different phases of the transcription cycle, RNA polymerase (Pol) II recruits various factors via...