Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection.

Tat-vaccinated macaques do not control simian immunodeficiency virus SIVmac239 replication

T. M. ALLEN
B. MOTH
M. LIEBL
P. JING
B. CALORE
M. PIEKARCZYK
R. RUDDERSDORF
D. H. OCONNOR
X. WANG
C. X. WANG
D. B. ALLISON
J. D. ALTMAN
A. SETTE
R. DESROSIERS
G. SUTTER
D. I. WATKINS
MORTARA, LORENZO

January 2002

The regulatory proteins of human immunodeficiency virus may represent important vaccine targets. Her...

Effective induction of simian immunodeficiency virus-specific cytotoxic T lymphocytes in macaques by using a multiepitope gene and DNA prime-modified vaccinia virus Ankara boost vaccination regimen.

Hanke, T
Samuel, RV
Blanchard, TJ
Neumann, VC
Allen, TM
Boyson, JE
Sharpe, SA
Cook, N
Smith, GL
Watkins, DI
Cranage, MP
Mcmichael, AJ

September 1999

DNA and modified vaccinia virus Ankara (MVA) are vaccine vehicles suitable and safe for use in human...

Positive role of macaque cytotoxic T lymphocytes during SIV infection: decrease of cellular viremia and increase of asymptomatic clinical period.

I. BOURGAULT-VILLADA
L. MORTARA
A.M. AUBERTIN
H. GRAS-MASSE
J.P. LVY
J.G. GUILLET

January 1997

We have measured cellular viremia and observed clinical outcome of macaques from two cohorts, the fi...

Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection.

Allen, TM
Jing, P
Calore, B
Horton, H
O'Connor, DH
Hanke, T
Piekarczyk, M
Ruddersdorf, R
Mothé, BR
Emerson, C
Wilson, N
Lifson, JD
Belyakov, IM
Berzofsky, JA
Wang, C
Allison, DB
Montefiori, DC
Desrosiers, RC
Wolinsky, S
Kunstman, KJ
Altman, JD
Sette, A
Mcmichael, AJ
Watkins, DI

October 2002

Vaccine-induced cytotoxic T lymphocytes (CTL) have been implicated in the control of virus replicati...

Virus replication and evolution drive the kinetics and specificity of SIV-specific cytotoxic T lymphocyte.

Geretti, Anna Maria
Osterhaus, Albert

December 2001

textabstractSIV (simian immunodeficiency virus) infection of cynomolgus macaques provides an excelle...

Cytotoxic T-cell response to simian immunodeficiency virus by cynomolgus macaque monkeys immunized with recombinant vaccinia virus.

Gotch, F
Hovell, R
Delchambre, M
Silvera, P
Mcmichael, A

January 1991

Simian immunodeficiency virus (SIV) gag-specific major histocompatibility complex (MHC)-restricted c...

Multispecific vaccine-induced mucosal cytotoxic T lymphocytes reduce acute-phase viral replication but fail in long-term control of simian immunodeficiency virus SIVmac239.

Vogel, T.U.
Reynolds, M.R.
Fuller, D.H.
Vielhuber, K.
Shipley, T.
Fuller, J.T.
Kunstman, K.J.
Sutter, G.
Marthas, M.L.
Erfle, V.
Wolinsky, S.M.
Wang, C.
Allison, D.B.
Rud, E.W.
Wilson, N.
Montefiori, D.
Altman, J.D.
Watkins, D.I.

January 2003

Given the current difficulties generating vaccine-induced neutralizing antibodies to human immunodef...

Simian immunodeficiency virus-specific cytotoxic T lymphocytes and protection against challenge in rhesus macaques immunized with a live attenuated simian immunodeficiency virus vaccine.

Nixon, DF
Donahoe, SM
Kakimoto, WM
Samuel, RV
Metzner, KJ
Gettie, A
Hanke, T
Marx, PA
Connor, RI

January 2000

In this study, we examined the role of simian immunodeficiency virus (SIV)-specific cytotoxic T lymp...

Simian immunodeficiency virus (SIV)-specific CD8+ cytotoxic T lymphocyte responses of naive and vaccinated cynomolgus macaques infected with (SIV)mac32H(J5): quantitative analysis by in vitro antigenic stimulation.

Geretti, Anna Maria
Hulskotte, Ellen
Dings, Marlinda
Baalen, Carel
Amerongen, Geert
Osterhaus, Albert

January 1997

textabstractDetailed analyses of simian immunodeficiency virus (SIV)-specific cytotoxic T lymphocyte...

Early suppression of SIV replication by CD8+ nef-specific cytotoxic T cells in vaccinated macaques

Gallimore, Awen Myfanwy
Cranage, M.
Cook, N.
Almond, N.
Bootman, J.
Rud, E.
Silvera, P.
Dennis, M.
Corcoran, T.
Stott, J.

November 1995

In order to develop a successful subunit vaccine against infection with the human immunodeficiency v...

Simian Immunodeficiency Virus-Specific Cytotoxic T Lymphocytes and Protection Against Challenge in Rhesus Macaques Immunized with a Live Attenuated Simian Immunodeficiency Virus Vaccine

Nixon, Douglas F.
Donahoe, Sean M.
Kakimoto, William M.
Samuel, Rachel V.
Metzner, Karin J.
Gettie, Agegnehu
Hanke, Tomas
Marx, Preston A.
Connor, Ruth I.

January 2000

AbstractIn this study, we examined the role of simian immunodeficiency virus (SIV)-specific cytotoxi...

Characterization of an Effective CTL Response against HIV and SIV Infections

Meritxell Genescà

April 2020

A vaccine inducing protective immunity in mucosal tissues and secretions may stop or limit HIV infec...

Induction of simian immunodeficiency virus (SIV)-specific CTL in rhesus macaques by vaccination with modified vaccinia virus Ankara expressing SIV transgenes: influence of pre-existing anti-vector immunity.

Sharpe, S
Polyanskaya, N
Dennis, M
Sutter, G
Hanke, T
Erfle, V
Hirsch, V
Cranage, M

January 2001

A major aim in AIDS vaccine development is the definition of strategies to stimulate strong and dura...

A Vaccine-Elicited, Single Viral Epitope-Specific Cytotoxic T Lymphocyte Response Does Not Protect against Intravenous,

Cell-free Simian
Immunodeficiency Virus Challenge
Emilio A. Emini
Anthony J. Conley
Norman L. Letvin

January 1994

Protection against simian immunodeficiency virus (SIV) challenge was assessed in rhesus monkeys with...

Maintenance or Emergence of Chronic Phase Secondary Cytotoxic T Lymphocyte Responses after Loss of Acute Phase Immunodominant Responses Does Not Protect SIV-Infected Rhesus Macaques from Disease Progression

M. Shannon Keckler
Vida L. Hodara
Laura M. Parodi
Luis D. Giavedoni

January 2010

The simian immunodeficiency virus- (SIV-) infected rhesus macaque is the preferred animal model for ...

Tat-vaccinated macaques do not control simian immunodeficiency virus SIVmac239 replication

T. M. ALLEN
B. MOTH
M. LIEBL
P. JING
B. CALORE
M. PIEKARCZYK
R. RUDDERSDORF
D. H. OCONNOR
X. WANG
C. X. WANG
D. B. ALLISON
J. D. ALTMAN
A. SETTE
R. DESROSIERS
G. SUTTER
D. I. WATKINS
MORTARA, LORENZO

January 2002

The regulatory proteins of human immunodeficiency virus may represent important vaccine targets. Her...

Effective induction of simian immunodeficiency virus-specific cytotoxic T lymphocytes in macaques by using a multiepitope gene and DNA prime-modified vaccinia virus Ankara boost vaccination regimen.

Hanke, T
Samuel, RV
Blanchard, TJ
Neumann, VC
Allen, TM
Boyson, JE
Sharpe, SA
Cook, N
Smith, GL
Watkins, DI
Cranage, MP
Mcmichael, AJ

September 1999

DNA and modified vaccinia virus Ankara (MVA) are vaccine vehicles suitable and safe for use in human...

Positive role of macaque cytotoxic T lymphocytes during SIV infection: decrease of cellular viremia and increase of asymptomatic clinical period.

I. BOURGAULT-VILLADA
L. MORTARA
A.M. AUBERTIN
H. GRAS-MASSE
J.P. LVY
J.G. GUILLET

January 1997

We have measured cellular viremia and observed clinical outcome of macaques from two cohorts, the fi...

Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection.

Allen, TM
Jing, P
Calore, B
Horton, H
O'Connor, DH
Hanke, T
Piekarczyk, M
Ruddersdorf, R
Mothé, BR
Emerson, C
Wilson, N
Lifson, JD
Belyakov, IM
Berzofsky, JA
Wang, C
Allison, DB
Montefiori, DC
Desrosiers, RC
Wolinsky, S
Kunstman, KJ
Altman, JD
Sette, A
Mcmichael, AJ
Watkins, DI

October 2002

Vaccine-induced cytotoxic T lymphocytes (CTL) have been implicated in the control of virus replicati...

Virus replication and evolution drive the kinetics and specificity of SIV-specific cytotoxic T lymphocyte.

Geretti, Anna Maria
Osterhaus, Albert

December 2001

textabstractSIV (simian immunodeficiency virus) infection of cynomolgus macaques provides an excelle...

Cytotoxic T-cell response to simian immunodeficiency virus by cynomolgus macaque monkeys immunized with recombinant vaccinia virus.

Gotch, F
Hovell, R
Delchambre, M
Silvera, P
Mcmichael, A

January 1991

Simian immunodeficiency virus (SIV) gag-specific major histocompatibility complex (MHC)-restricted c...

Multispecific vaccine-induced mucosal cytotoxic T lymphocytes reduce acute-phase viral replication but fail in long-term control of simian immunodeficiency virus SIVmac239.

Vogel, T.U.
Reynolds, M.R.
Fuller, D.H.
Vielhuber, K.
Shipley, T.
Fuller, J.T.
Kunstman, K.J.
Sutter, G.
Marthas, M.L.
Erfle, V.
Wolinsky, S.M.
Wang, C.
Allison, D.B.
Rud, E.W.
Wilson, N.
Montefiori, D.
Altman, J.D.
Watkins, D.I.

January 2003

Given the current difficulties generating vaccine-induced neutralizing antibodies to human immunodef...

Simian immunodeficiency virus-specific cytotoxic T lymphocytes and protection against challenge in rhesus macaques immunized with a live attenuated simian immunodeficiency virus vaccine.

Nixon, DF
Donahoe, SM
Kakimoto, WM
Samuel, RV
Metzner, KJ
Gettie, A
Hanke, T
Marx, PA
Connor, RI

January 2000

In this study, we examined the role of simian immunodeficiency virus (SIV)-specific cytotoxic T lymp...

Simian immunodeficiency virus (SIV)-specific CD8+ cytotoxic T lymphocyte responses of naive and vaccinated cynomolgus macaques infected with (SIV)mac32H(J5): quantitative analysis by in vitro antigenic stimulation.

Geretti, Anna Maria
Hulskotte, Ellen
Dings, Marlinda
Baalen, Carel
Amerongen, Geert
Osterhaus, Albert

January 1997

textabstractDetailed analyses of simian immunodeficiency virus (SIV)-specific cytotoxic T lymphocyte...

Early suppression of SIV replication by CD8+ nef-specific cytotoxic T cells in vaccinated macaques

Gallimore, Awen Myfanwy
Cranage, M.
Cook, N.
Almond, N.
Bootman, J.
Rud, E.
Silvera, P.
Dennis, M.
Corcoran, T.
Stott, J.

November 1995

In order to develop a successful subunit vaccine against infection with the human immunodeficiency v...

Simian Immunodeficiency Virus-Specific Cytotoxic T Lymphocytes and Protection Against Challenge in Rhesus Macaques Immunized with a Live Attenuated Simian Immunodeficiency Virus Vaccine

Nixon, Douglas F.
Donahoe, Sean M.
Kakimoto, William M.
Samuel, Rachel V.
Metzner, Karin J.
Gettie, Agegnehu
Hanke, Tomas
Marx, Preston A.
Connor, Ruth I.

January 2000

AbstractIn this study, we examined the role of simian immunodeficiency virus (SIV)-specific cytotoxi...

Characterization of an Effective CTL Response against HIV and SIV Infections

Meritxell Genescà

April 2020

A vaccine inducing protective immunity in mucosal tissues and secretions may stop or limit HIV infec...

Induction of simian immunodeficiency virus (SIV)-specific CTL in rhesus macaques by vaccination with modified vaccinia virus Ankara expressing SIV transgenes: influence of pre-existing anti-vector immunity.

Sharpe, S
Polyanskaya, N
Dennis, M
Sutter, G
Hanke, T
Erfle, V
Hirsch, V
Cranage, M

January 2001

A major aim in AIDS vaccine development is the definition of strategies to stimulate strong and dura...

A Vaccine-Elicited, Single Viral Epitope-Specific Cytotoxic T Lymphocyte Response Does Not Protect against Intravenous,

Cell-free Simian
Immunodeficiency Virus Challenge
Emilio A. Emini
Anthony J. Conley
Norman L. Letvin

January 1994

Protection against simian immunodeficiency virus (SIV) challenge was assessed in rhesus monkeys with...

Maintenance or Emergence of Chronic Phase Secondary Cytotoxic T Lymphocyte Responses after Loss of Acute Phase Immunodominant Responses Does Not Protect SIV-Infected Rhesus Macaques from Disease Progression

M. Shannon Keckler
Vida L. Hodara
Laura M. Parodi
Luis D. Giavedoni

January 2010

The simian immunodeficiency virus- (SIV-) infected rhesus macaque is the preferred animal model for ...

Tat-vaccinated macaques do not control simian immunodeficiency virus SIVmac239 replication

T. M. ALLEN
B. MOTH
M. LIEBL
P. JING
B. CALORE
M. PIEKARCZYK
R. RUDDERSDORF
D. H. OCONNOR
X. WANG
C. X. WANG
D. B. ALLISON
J. D. ALTMAN
A. SETTE
R. DESROSIERS
G. SUTTER
D. I. WATKINS
MORTARA, LORENZO

January 2002

The regulatory proteins of human immunodeficiency virus may represent important vaccine targets. Her...

Effective induction of simian immunodeficiency virus-specific cytotoxic T lymphocytes in macaques by using a multiepitope gene and DNA prime-modified vaccinia virus Ankara boost vaccination regimen.

Hanke, T
Samuel, RV
Blanchard, TJ
Neumann, VC
Allen, TM
Boyson, JE
Sharpe, SA
Cook, N
Smith, GL
Watkins, DI
Cranage, MP
Mcmichael, AJ

September 1999

DNA and modified vaccinia virus Ankara (MVA) are vaccine vehicles suitable and safe for use in human...

Positive role of macaque cytotoxic T lymphocytes during SIV infection: decrease of cellular viremia and increase of asymptomatic clinical period.

I. BOURGAULT-VILLADA
L. MORTARA
A.M. AUBERTIN
H. GRAS-MASSE
J.P. LVY
J.G. GUILLET

January 1997

We have measured cellular viremia and observed clinical outcome of macaques from two cohorts, the fi...

Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection.

Abstract

Extracted data

Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection.

Abstract

Extracted data

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