Comparison of IgM, IgG1 and IgG2 responses to

Pigs infected with T. spiralis and T. britovi were followed by double (lgG) and triple antibody ELISA (IgG1, lgG 2 and IgM) during a 12-week-period. Specific IgG and IgG1 responses were similar and showed a significant relation with the infecting doses and intensity of infection. Response to T. britovi was slightly lower than in groups infected with the same dose of T. spiralis. lgG 2 response was weak and almost undetectable in the lowest infected pigs, but relationship with the intensity of infection was unclear. IgM antibodies showed rapid but transient increases, generally simultaneous to peaks of IgG response