An efficient, catalyst free, 1,3-dipolar cycloaddition strategy to conjugate nucleosides and nucleotides with isoxazoles under atmospheric conditions and in an aqueous environment is reported. The protocol involves chloramine-T as a practical reagent to induce in situ nitrile oxide formation and the alkyne partner is attached to the sugar residue or the nucleobase. The reactions are regiospecific, fast and high yielding
In this paper, we report the regioselective synthesis of 3,5‐disubstituted isoxazoles by 1,3‐dipolar...
In this paper, we report the regioselective synthesis of 3,5‐disubstituted isoxazoles by 1,3‐dipolar...
A fast and practical metal free conjugation of ribonucleosides and 2¢-OMe 4-mer oligoribonucleotides...
An efficient, catalyst free, 1,3-dipolar cycloaddition strategy to conjugate nucleosides and nucleot...
An efficient, catalyst free, 1,3-dipolar cycloaddition strategy to conjugate nucleosides and nucleot...
The versatility of the isoxazole generating nitrile oxide–alkyne Huisgen cycloaddition for provision...
Bioconjugation protocols in environments free from residual copper or other catalytic components ar...
The ultimate goal of the novel work discussed in this Ph.D. thesis was the synthesIs of a range of c...
The ultimate goal of the novel work discussed in this Ph.D. thesis was the synthesIs of a range of c...
The focus of the novel research reported in this thesis is the labelling of nucleic acids by catalys...
The focus of the novel research reported in this thesis is the labelling of nucleic acids by catalys...
The focus of the novel research reported in this thesis is the labelling of nucleic acids by catalys...
Solid-phase oligonucleotide conjugation by nitrile oxide–alkyne click cycloaddition chemistry has b...
In this paper, we report the regioselective synthesis of 3,5‐disubstituted isoxazoles by 1,3‐dipolar...
In this paper, we report the regioselective synthesis of 3,5‐disubstituted isoxazoles by 1,3‐dipolar...
In this paper, we report the regioselective synthesis of 3,5‐disubstituted isoxazoles by 1,3‐dipolar...
In this paper, we report the regioselective synthesis of 3,5‐disubstituted isoxazoles by 1,3‐dipolar...
A fast and practical metal free conjugation of ribonucleosides and 2¢-OMe 4-mer oligoribonucleotides...
An efficient, catalyst free, 1,3-dipolar cycloaddition strategy to conjugate nucleosides and nucleot...
An efficient, catalyst free, 1,3-dipolar cycloaddition strategy to conjugate nucleosides and nucleot...
The versatility of the isoxazole generating nitrile oxide–alkyne Huisgen cycloaddition for provision...
Bioconjugation protocols in environments free from residual copper or other catalytic components ar...
The ultimate goal of the novel work discussed in this Ph.D. thesis was the synthesIs of a range of c...
The ultimate goal of the novel work discussed in this Ph.D. thesis was the synthesIs of a range of c...
The focus of the novel research reported in this thesis is the labelling of nucleic acids by catalys...
The focus of the novel research reported in this thesis is the labelling of nucleic acids by catalys...
The focus of the novel research reported in this thesis is the labelling of nucleic acids by catalys...
Solid-phase oligonucleotide conjugation by nitrile oxide–alkyne click cycloaddition chemistry has b...
In this paper, we report the regioselective synthesis of 3,5‐disubstituted isoxazoles by 1,3‐dipolar...
In this paper, we report the regioselective synthesis of 3,5‐disubstituted isoxazoles by 1,3‐dipolar...
In this paper, we report the regioselective synthesis of 3,5‐disubstituted isoxazoles by 1,3‐dipolar...
In this paper, we report the regioselective synthesis of 3,5‐disubstituted isoxazoles by 1,3‐dipolar...
A fast and practical metal free conjugation of ribonucleosides and 2¢-OMe 4-mer oligoribonucleotides...