Variation in amino acid sequences on a disulfide-linked polypeptide backbone generates differing pK(a) vectors for DNA delivery, which release nucleic acids under reducing conditions and transfect cells with greater efficacy than non-reducible or non-variable pK(a) analogues
Modification (%) means the percentage of modified amine/total amine. Various non-viral gene delivery...
A group of new disulfide-containing poly(β-amino ester)s was synthesized and evaluated as non-viral ...
© 2017 American Chemical Society. The rational design of gene vectors relies on the understanding of...
Xiaoyu Wang,1,2* Zongguang Tai,1* Jing Tian,1* Wei Zhang,3 Chong Yao,1 Lijuan Zhang,1 Yuan Gao,1 Qua...
A bioreducible poly(amido amine) (SS-PAA) gene carrier, known as poly (amido-butanol) (pABOL), was u...
We have evaluated the capacity of the cell-binding heptapeptide SIGYPLP to enhance transgene express...
Tuning a gene delivery vector: the role of peptide sequence and peptide branching in delivering of D...
Chong Yao,1,* Zongguang Tai,1,* Xiaoyu Wang,1,* Jiyong Liu,1 Quangang Zhu,1,2 Xin Wu,3 Lijuan Zhang,...
Gene therapy can be defined as the introduction of exogenous nucleic acids into cells with the inte...
Gene delivery is the science of transferring genetic material into cells by means of a vector to alt...
Genetic vaccines offer a treatment opportunity based upon successful gene delivery to specific immun...
Gene therapy is emerging as a revolutionary alternative to conventional therapeutic approaches. Howe...
This thesis describes a new platform technology. The technique is referred to as Bioplex (biological...
International audienceNucleic acid delivery constitutes an emerging therapeutic strategy to cure var...
Modification (%) means the percentage of modified amine/total amine. Various non-viral gene delivery...
A group of new disulfide-containing poly(β-amino ester)s was synthesized and evaluated as non-viral ...
© 2017 American Chemical Society. The rational design of gene vectors relies on the understanding of...
Xiaoyu Wang,1,2* Zongguang Tai,1* Jing Tian,1* Wei Zhang,3 Chong Yao,1 Lijuan Zhang,1 Yuan Gao,1 Qua...
A bioreducible poly(amido amine) (SS-PAA) gene carrier, known as poly (amido-butanol) (pABOL), was u...
We have evaluated the capacity of the cell-binding heptapeptide SIGYPLP to enhance transgene express...
Tuning a gene delivery vector: the role of peptide sequence and peptide branching in delivering of D...
Chong Yao,1,* Zongguang Tai,1,* Xiaoyu Wang,1,* Jiyong Liu,1 Quangang Zhu,1,2 Xin Wu,3 Lijuan Zhang,...
Gene therapy can be defined as the introduction of exogenous nucleic acids into cells with the inte...
Gene delivery is the science of transferring genetic material into cells by means of a vector to alt...
Genetic vaccines offer a treatment opportunity based upon successful gene delivery to specific immun...
Gene therapy is emerging as a revolutionary alternative to conventional therapeutic approaches. Howe...
This thesis describes a new platform technology. The technique is referred to as Bioplex (biological...
International audienceNucleic acid delivery constitutes an emerging therapeutic strategy to cure var...
Modification (%) means the percentage of modified amine/total amine. Various non-viral gene delivery...
A group of new disulfide-containing poly(β-amino ester)s was synthesized and evaluated as non-viral ...
© 2017 American Chemical Society. The rational design of gene vectors relies on the understanding of...