SUMMARY: There is an immediate need for tools to both analyse and visualize in real-time single-nucleotide polymorphisms, insertions and deletions, and other structural variants from new sequence file formats. We have developed VarB software that can be used to visualize variant call format files in real time, as well as identify regions under balancing selection and informative markers to differentiate user-defined groups (e.g. populations). We demonstrate its utility using sequence data from 50 Plasmodium falciparum isolates comprising two different continents and confirm known signals from genomic regions that contain important antigenic and anti-malarial drug-resistance genes. AVAILABILITY AND IMPLEMENTATION: The C++-based software VarB...
Plasmodium vivax, one of the five species of Plasmodium parasites that cause human ma-laria, is resp...
MalariaGEN is a data-sharing network that enables groups around the world to work together on the ge...
Background. Most genetic disorders are caused by single nucleotide variations (SNVs) or small insert...
SUMMARY: There is an immediate need for tools to both analyse and visualize in real-time single-nucl...
High throughput sequencing is generating large datasets that can be used provide important insights ...
Malaria is a global public health challenge, with drug resistance a major barrier to disease control...
VarB: a variation browsing and analysis tool for variants derived from next-generation sequencing da...
International audienceWith the rapidly developing high-throughput sequencing technologies known as n...
International audiencePlasmodium vivax, one of the five species of Plasmodium parasites that cause h...
MalariaGEN is a data-sharing network that enables groups around the world to work together on the ge...
Plasmodium vivax, one of the five species of Plasmodium parasites that cause human malaria, is respo...
Background: Since the advent of next-generation sequencing many previously untestable hypotheses hav...
MalariaGEN is a data-sharing network that enables groups around the world to work together on the ge...
Malaria elimination strategies require surveillance of the parasite population for genetic changes t...
Individuals living in endemic areas generally harbour multiple parasite strains. Multiplicity of inf...
Plasmodium vivax, one of the five species of Plasmodium parasites that cause human ma-laria, is resp...
MalariaGEN is a data-sharing network that enables groups around the world to work together on the ge...
Background. Most genetic disorders are caused by single nucleotide variations (SNVs) or small insert...
SUMMARY: There is an immediate need for tools to both analyse and visualize in real-time single-nucl...
High throughput sequencing is generating large datasets that can be used provide important insights ...
Malaria is a global public health challenge, with drug resistance a major barrier to disease control...
VarB: a variation browsing and analysis tool for variants derived from next-generation sequencing da...
International audienceWith the rapidly developing high-throughput sequencing technologies known as n...
International audiencePlasmodium vivax, one of the five species of Plasmodium parasites that cause h...
MalariaGEN is a data-sharing network that enables groups around the world to work together on the ge...
Plasmodium vivax, one of the five species of Plasmodium parasites that cause human malaria, is respo...
Background: Since the advent of next-generation sequencing many previously untestable hypotheses hav...
MalariaGEN is a data-sharing network that enables groups around the world to work together on the ge...
Malaria elimination strategies require surveillance of the parasite population for genetic changes t...
Individuals living in endemic areas generally harbour multiple parasite strains. Multiplicity of inf...
Plasmodium vivax, one of the five species of Plasmodium parasites that cause human ma-laria, is resp...
MalariaGEN is a data-sharing network that enables groups around the world to work together on the ge...
Background. Most genetic disorders are caused by single nucleotide variations (SNVs) or small insert...