The versatility of 3,4-O-isopropylidene-2-C-methyl-d-arabinonolactone [from d-erythronolactone] as a chiron for complex piperidines and pyrrolidines is illustrated by the synthesis of (2R,3S,4S)- and (2R,3S,4R)-dihydroxy-2-C-methyl prolines, 1,4-dideoxy-1,4-imino-4-C-methyl-l-ribitol and 1,4-dideoxy-1,4-imino-4-C-methyl-l-arabinitol, and isofagomine derivatives; the enantiomeric series is equally accessible from l-erythronolactone. © 2008 Elsevier Ltd. All rights reserved
The use of carbohydrates as starting materials for organic synthesis is illustrated by the synthesis...
International audienceScalable synthesis of enantiopure ( R ) and ( S )-α-Tfm-proline and α-Tfm-pipe...
The use of readily available sugar lactones in the synthesis of polyhydroxylated pyrrolidines is ill...
The versatility of 3,4-O-isopropylidene-2-C-methyl-d-arabinonolactone [from d-erythronolactone] as a...
Readily crystallized 2-C-methyl-d-ribono-1,4-lactone is formed in a one-pot procedure from d-glucose...
Two carbon chain extensions using a Wittig reaction on both a 1-deoxy ribulose derivative and a C-2-...
The synthesis of a new chiral pyrrolidine has been performed using 2,3-O-isopropylidene-D-erythronol...
The title bicyclic lactone, C(19)H(19)NO(3), is an inter-mediate in the synthesis of chiral α-methyl...
M.Sc. (Chemistry)The aim of this study waa to develop new methodology for the synthesis of chiral py...
A synthesis of 2R,3S,4R-dihydroxyproline is described in which an azide is introduced into C-2 posit...
The straightforward synthesis of pyrrolo[3,4-b]quinolone and pyrrolo[3,2-b]quinolone backbones, whic...
A versatile approach to enantiopure (4S, 5R)-5-alkyl-4-hydroxy-2-pyrrolidinones is described. The ke...
A suitable methodology is outlined for the production of optically active (alpha)-hydroxy amide deri...
[eng] 1. (R)-Phenylglycinol-derived oxazolopiperidone lactams can be converted to enantiopure open-c...
An acetonide is the only protecting group used in the synthesis of both the enantiomers of 2,4-di-C-...
The use of carbohydrates as starting materials for organic synthesis is illustrated by the synthesis...
International audienceScalable synthesis of enantiopure ( R ) and ( S )-α-Tfm-proline and α-Tfm-pipe...
The use of readily available sugar lactones in the synthesis of polyhydroxylated pyrrolidines is ill...
The versatility of 3,4-O-isopropylidene-2-C-methyl-d-arabinonolactone [from d-erythronolactone] as a...
Readily crystallized 2-C-methyl-d-ribono-1,4-lactone is formed in a one-pot procedure from d-glucose...
Two carbon chain extensions using a Wittig reaction on both a 1-deoxy ribulose derivative and a C-2-...
The synthesis of a new chiral pyrrolidine has been performed using 2,3-O-isopropylidene-D-erythronol...
The title bicyclic lactone, C(19)H(19)NO(3), is an inter-mediate in the synthesis of chiral α-methyl...
M.Sc. (Chemistry)The aim of this study waa to develop new methodology for the synthesis of chiral py...
A synthesis of 2R,3S,4R-dihydroxyproline is described in which an azide is introduced into C-2 posit...
The straightforward synthesis of pyrrolo[3,4-b]quinolone and pyrrolo[3,2-b]quinolone backbones, whic...
A versatile approach to enantiopure (4S, 5R)-5-alkyl-4-hydroxy-2-pyrrolidinones is described. The ke...
A suitable methodology is outlined for the production of optically active (alpha)-hydroxy amide deri...
[eng] 1. (R)-Phenylglycinol-derived oxazolopiperidone lactams can be converted to enantiopure open-c...
An acetonide is the only protecting group used in the synthesis of both the enantiomers of 2,4-di-C-...
The use of carbohydrates as starting materials for organic synthesis is illustrated by the synthesis...
International audienceScalable synthesis of enantiopure ( R ) and ( S )-α-Tfm-proline and α-Tfm-pipe...
The use of readily available sugar lactones in the synthesis of polyhydroxylated pyrrolidines is ill...