To determine the effects that mutation of the cystic fibrosis transmembrane conductance regulator (CFTR) gene and deletion of the glutathione S-transferase (GST) genes mu-1 (GSTM1) and theta-1 (GSTT1) have on the clinical course of cystic fibrosis (CF) in patients residing in the southeastern region of Brazil. The study sample consisted of all consecutive CF patients treated at the Hospital de Clínicas School of Medical Sciences of the State University at Campinas between March of 2002 and March of 2005. We included 66 CF patients. Genomic DNA was analyzed by polymerase chain reaction and restriction endonuclease digestion for the identification of the genotypes. The DF508 mutation of the CFTR gene was found in 44 patients (66.7%). The null...
Cystic fibrosis (CF) is the most common genetic disease among Caucasians and is rare among sub-Sahar...
Cystic fibrosis (CF) is the most common genetic disease among Caucasians and is rare among sub-Sahar...
AbstractBackgroundCystic fibrosis (CF) is produced by mutations in the Cystic Fibrosis Transmembrane...
OBJETIVO: Determinar os efeitos que a mutação do gene cystic fibrosis transmembrane conductance regu...
To verify the presence of ΔF508 mutation in the cystic fibrosis transmembrane conductance regulator ...
Abstract To define mutations present in 23 exons and flanking intronic sequences of the cystic fibro...
Cystic fibrosis (CF) is the most common autosomal recessive disease of the Caucasian population. Amo...
Objective: To verify the presence of δF508 mutation in the cystic fibrosis transmembrane conductance...
OBJETIVO: Verificar a presença da mutação ΔF508 no gene cystic fibrosis transmembrane conductan...
OBJECTIVE: To verify the presence of ΔF508 mutation in the cystic fibrosis transmembrane conduc...
We have performed molecular genetic analyses on 160 Brazilian patients diagnosed with cystic fibrosi...
The nature and frequency of cystic fibrosis mutations in Brazil is not uniform due to the highly var...
We have performed molecular genetic analyses on 160 Brazilian patients diagnosed with cystic fibrosi...
AbstractCystic Fibrosis (CF) is one of the most common single-gene defects in European descent popul...
Cystic fibrosis (CF), an autosomal recessive genetic disease, is recognized as one of the most preva...
Cystic fibrosis (CF) is the most common genetic disease among Caucasians and is rare among sub-Sahar...
Cystic fibrosis (CF) is the most common genetic disease among Caucasians and is rare among sub-Sahar...
AbstractBackgroundCystic fibrosis (CF) is produced by mutations in the Cystic Fibrosis Transmembrane...
OBJETIVO: Determinar os efeitos que a mutação do gene cystic fibrosis transmembrane conductance regu...
To verify the presence of ΔF508 mutation in the cystic fibrosis transmembrane conductance regulator ...
Abstract To define mutations present in 23 exons and flanking intronic sequences of the cystic fibro...
Cystic fibrosis (CF) is the most common autosomal recessive disease of the Caucasian population. Amo...
Objective: To verify the presence of δF508 mutation in the cystic fibrosis transmembrane conductance...
OBJETIVO: Verificar a presença da mutação ΔF508 no gene cystic fibrosis transmembrane conductan...
OBJECTIVE: To verify the presence of ΔF508 mutation in the cystic fibrosis transmembrane conduc...
We have performed molecular genetic analyses on 160 Brazilian patients diagnosed with cystic fibrosi...
The nature and frequency of cystic fibrosis mutations in Brazil is not uniform due to the highly var...
We have performed molecular genetic analyses on 160 Brazilian patients diagnosed with cystic fibrosi...
AbstractCystic Fibrosis (CF) is one of the most common single-gene defects in European descent popul...
Cystic fibrosis (CF), an autosomal recessive genetic disease, is recognized as one of the most preva...
Cystic fibrosis (CF) is the most common genetic disease among Caucasians and is rare among sub-Sahar...
Cystic fibrosis (CF) is the most common genetic disease among Caucasians and is rare among sub-Sahar...
AbstractBackgroundCystic fibrosis (CF) is produced by mutations in the Cystic Fibrosis Transmembrane...