Reference intervals for saliva analytes collected by a standardized method in a physically active population

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Objectives: Our aims were to test a liquid-based saliva collection system for total antioxidant status (TAS), uric acid (UA), total protein concentration (TP) and salivary alpha-amylase (SAA) activity; to determine if these analytes in serum and saliva are correlated in a physically active population and to establish reference intervals for these parameters. Design and methods: Participants in this study were 115 physically active males (18-20 years old). Saliva samples were collected using the Saliva Collection System (Greiner Bio-One (R)) immediately before obtaining blood. Biochemical analyses were conducted using an Autolab Boehringer analyzer. Results: We found a correlation between UA and TP concentrations in serum and saliva samples. The reference intervals for TP and SAA activity in the morning were lower than in the afternoon (p