I consider a class of fitness landscapes, in which the fitness is a function of a finite number of phenotypic “traits”, which are themselves linear functions of the genotype. I show that the stationary trait distribution in such a landscape can be explicitly evaluated in a suitably defined “thermodynamic limit”, which is a combination of infinite-genome and strong selection limits. These considerations can be applied in particular to identify relevant features of the evolution of promoter binding sites, in spite of the shortness of the corresponding sequences
We explore how the genotype–phenotype map determines convergent evolution in a simple model of spati...
This article is concerned with the evolution of haploid organisms that reproduce asexually. In a sem...
We consider the evolution of large but finite populations on arbitrary fitness landscapes. We descri...
Abstract. We study the adaptation dynamics of an initially maladapted population evolving via the el...
The mapping from genotype to phenotype to fitness typically involves multiple nonlinearities that ca...
Adaptation depends critically on the effects of new mutations and their dependency on the genetic ba...
Abstract: Evolution through mutation and selection in populations of asexu-ally replicating entities...
Understanding evolution on complex fitness landscapes is difficult both because of the large dimensi...
We discuss a population of sequences subject to mutations and frequency-dependent selection, where t...
In 1932 Sewall Wright introduced the notion of the fitness landscape. By analogy with a physical lan...
We analyze the evolution of a multidimensional quantitative trait in a class-structured focal specie...
The typical view in evolutionary biology is that mutation rates are minimised. Contrary to that view...
Understanding evolution on complex fitness landscapes is difficult both because of the large dimensi...
AbstractA quasispecies is a set of interrelated genotypes that have reached a stationary state while...
<p>Evolutionary dynamics can be notoriously complex and difficult to analyze. In this dissertation I...
We explore how the genotype–phenotype map determines convergent evolution in a simple model of spati...
This article is concerned with the evolution of haploid organisms that reproduce asexually. In a sem...
We consider the evolution of large but finite populations on arbitrary fitness landscapes. We descri...
Abstract. We study the adaptation dynamics of an initially maladapted population evolving via the el...
The mapping from genotype to phenotype to fitness typically involves multiple nonlinearities that ca...
Adaptation depends critically on the effects of new mutations and their dependency on the genetic ba...
Abstract: Evolution through mutation and selection in populations of asexu-ally replicating entities...
Understanding evolution on complex fitness landscapes is difficult both because of the large dimensi...
We discuss a population of sequences subject to mutations and frequency-dependent selection, where t...
In 1932 Sewall Wright introduced the notion of the fitness landscape. By analogy with a physical lan...
We analyze the evolution of a multidimensional quantitative trait in a class-structured focal specie...
The typical view in evolutionary biology is that mutation rates are minimised. Contrary to that view...
Understanding evolution on complex fitness landscapes is difficult both because of the large dimensi...
AbstractA quasispecies is a set of interrelated genotypes that have reached a stationary state while...
<p>Evolutionary dynamics can be notoriously complex and difficult to analyze. In this dissertation I...
We explore how the genotype–phenotype map determines convergent evolution in a simple model of spati...
This article is concerned with the evolution of haploid organisms that reproduce asexually. In a sem...
We consider the evolution of large but finite populations on arbitrary fitness landscapes. We descri...