Survival analysis of obese patients undergoing liver transplantation

Introduction. The influence of preoperative obesity in liver transplanted patients remains undetermined. Objective. To analyze the survival of obese patients undergoing liver transplantation. Methods. We calculated the body mass index (BMI; kg/m(2)) of 244 liver transplantation patients. All transplantations were performed from September 1991 to December 2006. The patients were divided according to the BMI values: nonobese (NO) patients (BMI 30). Pre- and postoperative data were used. The following statistical tests were employed: Student's t test, Kaplan-Meier survival, and Cox-Mantel tests. Results. Group O was composed of 38 individuals (15.3%) with BMI of 33.1, and the BMI of NO was 24. Group O showed an average age of 50.1 years and group NO, 45.5 years (P .05). A Cox proportional hazard analysis showed that the survival time in this study was related to red blood cell transfusions, recipient sodium, MELD score, donor sodium, and age. Recipient age was a main factor in multiple regression analysis for obese patients in this study. Conclusion. There was no significant difference between O and NO for the 1-year and long-term survivals, but older patients displayed lower survival times.39103225322