Quality Of Sleep And Quality Of Life In Adolescents Infected With Human Immunodeficiency Virus [qualidade Do Sono E Qualidade De Vida Em Adolescentes Infectados Pelo Vírus Da Imunodeficiência Humana]

Objectives: To assess sleep characteristics of adolescents infected by HIV, and to ascertain whether psychosocial aspects are associated to the quality of sleep. Methods: A cross-sectional study assessing 102 HIV-infected adolescents of both genders, aged between 10 and 20 years-old and 120 Controls. Data collection was performed by applying the Sleep Disturbance Scale for Children, the Epworth Sleepiness Scale, and the Pediatric Quality of Life Inventory. Results: A sleep disturbance prevalence of 77.4% was found in patients, and a 75% prevalence in controls, and there was correlation between quality of sleep and of life. HIV-infected adolescents scored higher for sleep breathing disorders and had higher prevalence of excessive daytime sleepiness. Conclusions: HIV-infected adolescents had similar quality of sleep compared to healthy adolescents. This may be explained by the steady improvements in daily living as a result of successful anti-retroviral therapy, and by the vulnerability that affects Brazilian adolescents living in major urban centers.706422427Carskadon, M.A., Sleep in adolescents: The perfect storm (2011) Pediatr Clin North Am, 58, pp. 637-647Owens, J.A., Belon, K., Moss, P., Impact of delaying school start time on adolescent sleep, mood, and behavior (2010) Arch Pediatr Adolesc Med, 164, pp. 608-614de-la-Llata-Romero, M., Castorena-Maldonado, A., Corsi-Cabrera, M., Sleep medicine: Development, contributions and perspectives Report of the work group on sleep medicine (2011) Rev Invest Clin, 63, pp. 90-99Mindell, J.A., Owens, J., Alves, R., Give children and adolescents the gift of a good night's sleep: A call to action (2011) Sleep Med, 12, pp. 203-204Moore, M., Meltzer, L.J., The sleepy adolescent: Causes and consequences of sleepiness in teens (2008) Paediatr Respir Rev, 9, pp. 114-120(2010) Global report: UNAIDS report on the global AIDS epidemic, , http://www.unaids.org/globalreport/documents/20101123_GlobalReport_full_en.pdf, Joint United Nations Programme on HIV/AIDS (UNAIDS), [cited 16 May 2011]. Available at(2011) Ministério da Saúde 2010, , http://www.aids.gov.br/publicacao/boletim-epidemiologico-2010, Brasil, Departamento de DST, Aids e Hepatites Virais. Boletim Epidemiológico AIDS 2010 (versão preliminar). [cited 21 March]. Available atHazra, R., Siberry, G.K., Mofenson, L.M., Growing up with HIV: Children, adolescents, and young adults with perinatally acquired HIV infection (2010) Ann Rev Med, 61, pp. 169-185Ramos, A.N., Matida, L.H., Hearst, N., Heukelbach, J., AIDS in Brazilian children: History, surveillance, antiretroviral therapy, and epidemiologic transition, 1984-2008 (2011) AIDS Patient Care STDS, 25, pp. 245-255Franck, L.S., Johnson, L.M., Lee, K., Sleep disturbances in children with human immunodeficiency virus infection (1999) Pediatrics, 104, pp. 1-5Reid, S., Dwyer, J., Insomnia in HIV Infection: A systematic review of prevalence, correlates and management (2005) Psychosomatic Med, 67, pp. 260-269Rocha, C.R.S., Rossini, S., Reimão, R., Sleep disorders in high school and pre-university students (2010) Arq Neuropsiquiatr, 68, pp. 903-907Mesquita, G., Reimão, R., Nightly use of computer by adolescents: Its effect on quality of sleep (2007) Arq Neuropsiquiatr, 65, pp. 428-432Varni, J.W., Seid, M., Rode, C.A., The PedsQL: Measurement model for the pediatric quality of life inventory (1999) Med Care, 37, pp. 126-139(2009) Ministério da Saúde, , Brasil, Secretaria de Vigilância em Saúde. Programa Nacional de DST e Aids. Recomendações para Terapia Antirretroviral em Crianças e Adolescentes Infectados polo HIV. Manual de bolso. Ministério da Saúde, Secretaria de Vigilância em Saúde, Programa Nacional de DST e Aids. Brasília: Ministério da SaúdeBruni, O., Salvatori, O., Guidetti, V., The sleep disturbance scale for children (SDSC) Construction and validation of an instrument to evaluate sleep disturbances in childhood and adolescence (1996) J Sleep Res, 5, pp. 251-261Johns, M.W., A new method for measuring daytime sleepiness: The Epworth sleepiness scale (1991) Sleep, 14, pp. 540-545Ferreira, V.R., Carvalho, L.B.C., Ruotolo, F., Morais, J.F., Prado, L.B.F., Prado, G.F., Sleep disturbance scale for children: Translation, cultural adaptation and validation (2009) Sleep Med, 10, pp. 457-463Bertolazi, N.A., Fagondes, S.C., Hoff, L.S., Pedro, V.D., Barreto, S.S.M., Johns, M.W., Validação da escala de sonolência de Epworth em português para uso no Brasil (2009) J Bras Pneumol, 35, pp. 877-883Klatchoian, D.A., Len, C.A., Terreri, M.T., Quality of life of children and adolescents from São Paulo: Reliability and validity of the Brazilian version of the Pediatric Quality of Life Inventory TM version 4.0 Generic Core Scales (2008) J Pediatr (Rio J), 84, pp. 308-315Potasz, C., Juliano, M.L., Varela, M.J., Prevalence of sleep disorders in children of a public hospital in São Paulo (2010) Arq Neuropsiquiatr, 68, pp. 235-241Carotenuto, M., Bruni, O., Santoro, N., Giudice, E.M., Perrone, L., Pascotto, A., Waist circumference predicts the occurrence of sleep-disordered breathing in obese children and adolescents: A questionnaire-based study (2006) Sleep Med, 7, pp. 357-361Ramalho, L.C.B., Gonçalves, E.M., Carvalho, W.R.G., Abnormalities in body composition and nutritional status in HIV-infected children and adolescents on antiretroviral therapy (2011) Int J STD AIDS, 22, pp. 453-456Chan, E.Y., Ng, D.K., Chan, C.H., Modified Epworth Sleepiness Scale in Chinese children with obstructive sleep apnea: A retrospective study (2009) Sleep Breath, 13, pp. 59-63Melendres, M.C., Lutz, J.M., Rubin, E.D., Marcus, C.L., Daytime sleepiness and hyperactivity in children with suspected sleep-disordered breathing (2004) Pediatrics, 114, pp. 768-775van Litsenburg, R.R., Huisman, J., Hoogerbrugge, P.M., Egeler, R.M., Kaspers, G.J., Gemke, R.J., Impaired sleep affects quality of life in children during maintenance treatment for acute lymphoblastic leukemia: An exploratory study (2011) Health Qual Life Outcomes, 18, pp. 9-25Erickson, J.M., Beck, S.L., Christian, B.R., Fatigue, sleep-wake disturbances, and quality of life in adolescents receiving chemotherapy (2011) J Pediatr Hematol Oncol, 33, pp. 17-25Mitchell, R.B., Boss, E.F., Pediatric obstructive sleep apnea in obese and normal-weight children: Impact of adenotonsillectomy on quality-of-life and behavior (2009) Dev Neuropsychol, 34, pp. 650-661Crabtree, V.M., Varni, J.W., Gozal, D., Health-related quality of life and depressive symptoms in children with suspected sleep-disordered breathing (2004) Sleep, 27, pp. 1131-1138Ong, L.C., Yang, W.W., Wong, S.W., Alsissiq, F., Khu, Y.S., Sleep habits and disturbances in Malaysian children with epilepsy (2010) J Paediatr Child Health, 46, pp. 80-8