Effects Of Cigarette Smoke Inhalation And Coffee Consumption On Bone Formation And Osseous Integration Of Hydroxyapatite Implant [os Efeitos Do Cigarro E Do Consumo De Café Sobre A Formação óssea E A Integração óssea De Implantes De Hidroxiapatita]
- Andrade A.R.
- Sant'Ana D.C.M.
- Mendes Junior J.A.
- Moreira M.
- Pires G.C.
- Santos M.P.
- Fernandes G.J.M.
- Nakagaki W.R.
- Garcia J.A.D.
- Lima C.C.
- Soares E.A.
DOIAbstract
The present study aims to assess the effects of cigarette smoke inhalation and/or coffee consumption on bone formation and osseous integration of a dense hydroxyapatite (D.HA) implant in rats. For this study, 20 male rats were divided into four groups (n = 5): C.T (control) group, C.E (coffee) group, C.I (cigarette) group and C.C (coffee + cigarette) group. During 16 weeks, animals in the C.I group were exposed to cigarette smoke inhalation equivalent to 6 cigarettes per day; specimens in the C.E group drank coffee as liquid diet; and rats in the C.C group were submitted to both substances. In the 6th week a 5 mm slit in the parietal bone and a 4 mm slit in the tibia were performed on the left side: the former was left open while the latter...
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