Optimum path forest-based classifiers are a novel approach for supervised pattern recognition. The OPF classifier differs from traditional approaches by not estimating probability density functions of the classes neither assuming samples linearity, and creates a discrete optimal partition of the feature space, in which the decision boundary is obtained by the influence zones of the most representative samples of the training set. Due to the large number of applications in biomedical signal processing involving pattern recognition techniques, specially voice disorders identification, we propose here the laryngeal pathology detection by means of OPF. Experiments were performed in three public datasets against SVM, and a comparison in terms of...