New Centrifugal Blood Pump With Dual Impeller And Double Pivot Bearing System: Wear Evaluation In Bearing System, Performance Tests, And Preliminary Hemolysis Tests

A new dual impeller centrifugal blood pump has been developed as a research collaboration between Baylor College of Medicine and Institute Dante Pazzanese of Cardiology for long-term left ventricle assist device (LVAD). A design feature of this new pump is a dual impeller that aims to minimize a stagnant flow pattern around the inlet port. Several different materials were tested in order to adopt a double pivot bearing design originally developed by Prof. Dr. Yukihiko Nosé from Baylor College of Medicine. Hydraulic performance tests were conducted with two different inlet ports' angle configurations 30° and 45°. Pump with inlet port angle of 45° achieved best values of pressure ahead and flow after 1800 rpm. Preliminary hemolysis tests were conducted using human blood. The pump showed good performance results and no alarming trace of hemolysis, proving to be a feasible long-term LVAD. © 2008, Copyright the Authors.324329333Andrade, A.J.P., Biscegli, J.F., Dinkhuysen, J., Characteristics of a blood pump combining the centrifugal and axial pump principles (1996) Artif Organs, 20, pp. 605-12Yamane, T., Miyamoto, Y., Tajima, K., Yamazaki, K., A comparative study between flow visualization and computational fluid dynamic analysis for the sun medical centrifugal blood pump (2004) Artif Organs, 28, pp. 458-66Ohara, Y., Sakuma, I., Makinouchi, K., Baylor Gyro pump: A completely seal-less centrifugal pump aiming for long-term circulatory support (1993) Artif Organs, 17, pp. 599-604Takami, Y., In vitro study to estimate particle release from a centrifugal blood pump (2006) Artif Organs, 30, pp. 371-6Takami, Y., Andrade, A.J.P., Nosé, Y., Eccentric inlet port of the pivot bearing supported Gyro centrifugal pump (1997) Artif Organs, 21, pp. 312-7Hansen, E., Bock, E., Nosé, Y., (2006) Miniaturized All-in-one Rpm-controllable Actuator for Gyro Centrifugal Blood Pump, , Proceeding of 52nd ASAIO Annual Conference. Chicago, IL, June 8-10Takami, Y., Nakazawa, T., Makinouchi, K., Benkowski, R., Glueck, J., Nosé, Y., Material of the double pivot bearing system in the Gyro C1E3 centrifugal pump (1997) Artif Organs, 21, pp. 143-7Andrade, A.J.P., Biscegli, J.F., Souza, J.E., Ohashi, Y., Nosé, Y., Flow visualization studies to improve the spiral pump design (1997) Artif Organs, 21, pp. 680-5Nosé, Y., Design and development strategy for the rotary blood pump (1998) Artif Organs, 22, pp. 438-4