The Complete Genome Sequence Of Chromobacterium Violaceum Reveals Remarkable And Exploitable Bacterial Adaptability

Ribeiro de Vasconcelos A.T.
De Almeida D.F.
Hungria M.
Guimaraes C.T.
Antonio R.V.
Cunha Almeida F.C.
De Almeida L.G.P.
De Almeida R.
Alves-Gomes J.A.
Mazoni Andrade E.M.
Araripe J.
De Araujo M.F.F.
Astolfi-Filho S.
Azevedo V.
Baptista A.J.
Mendes Bataus L.A.
Da Silva Batista J.
Belo A.
Van den Berg C.
Bogo M.
Bonatto S.
Bordignon J.
Macedo Brigidom M.M.
Alves Brito C.A.
Brocchi M.
Burity H.A.
Aranha Camargo A.
De Paula Cardoso D.D.D.
Carneiro N.P.
Carraro D.M.
Carvalho C.M.B.
De Mattos Cascardo J.C.D.M.
Sousa Cavada B.
Chueire L.M.O.
Beatriz Creczynski-Pasa T.
Costa Da Cunha-Junior N.C.
Fagundes N.
Lima Falao C.
Fantinatti F.
Farias I.P.
Felipe M.S.S.
Pereira Ferrari L.
Aparecido Ferro J.
Tiraboschi Ferro M.I.
Franco G.R.
Aguiar De Freitas N.S.
Furlan L.R.
Tostes Gazzinelli R.
Aparecida Gomes E.
Rodrigues Goncalves P.
Grangeiro T.B.
Grattapaglia D.
Grisard E.C.
Seixas Hanna E.
Neto Jardim S.
Laurino J.
Tenorio Leoi L.C.
Lima L.F.A.
Loureiro M.D.F.
Catanho Pereira de Lyra M.D.C.
Franca Madeira H.M.
Manfio G.P.
Queiroz Maranhao A.
Santos Martins W.
Zingaretti di Mauro S.M.
Batistuzzo de Medeiros S.R.
De Vasconcellos Meissner R.
Martins Moreira M.A.
Do Nascimento F.F.
Nicolas M.F.
Germano Oliveira J.
Costa Oliveira S.C.
Cury Paixao R.F.
Alves Parente J.
De Oliveira Pedrosa F.
Junho Penat S.D.
Odair Pereira J.
Pereira M.
Rodrigues Costa Pinto L.S.
Da SilvaPinto L.
Rebelo Porto J.I.
Porto Potrich D.
Ramalho-Neto C.E.
Moreira Reis A.M.
Um Rigo L.
Rondinelli E.
Pedraca do Santos E.B.
Santos F.R.
Cruz Schneider M.P.
Seuanez H.N.
Rodrigues Silva A.M.
Da Costa Da Silva A.L.
Wanderlei Silva D.
Silva R.
De Carmo Simoes I.
Simon D.
De Almeida Soares C.M.
Ascenco Soares R.D.B.

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Publication date

November 2015

DOI

10.1073/pnas.1832124100

Publisher

Proceedings of the National Academy of Sciences

Language

English

Abstract

Chromobacterium violaceum is one of millions of species of free-living microorganisms that populate the soil and water in the extant areas of tropical biodiversity around the world. Its complete genome sequence reveals (i) extensive alternative pathways for energy generation, (ii) ≈500 ORFs for transport-related proteins, (iii) complex and extensive systems for stress adaptation and motility, and (iv) wide-spread utilization of quorum sensing for control of inducible systems, all of which underpin the versatility and adaptability of the organism. The genome also contains extensive but incomplete arrays of ORFs coding for proteins associated with mammalian pathogenicity, possibly involved in the occasional but often fatal cases of human C. v...