Myoclonic Seizures In Symptomatic Temporal Lobe Epilepsy Of Childhood

Rationale and objective: Generalized epileptic manifestations may occur in symptomatic focal epilepsies in children, particularly in infants and pre-school children. Our aim here is to report two patients with myoclonic seizures associated with temporal lobe epilepsy. Methodology: Case report. Results: Two children with tumor in temporal lobe presented myoclonic seizures or spasms since infancy besides other types of seizures. Conclusion: Our findings support the idea that myoclonic seizures may be generalized manifestations of focal insults to the CNS, and this pattern may be an age-dependent specific response of a developing brain to a severe insult.1114547Faught, E., Clinical presentations and phenomenology of myoclonus (2003) Epilepsia, 44 (SUPPL. 11), pp. 7-12Hallet, M., Myoclonus and myoclonic syndromes (1997) Epilepsy: A comprensive textbook, pp. 2717-2723. , Engel J, Pedley, TA, editores, Philadelphia: Lippincott- Raven;Nordli, D.R., Kurada, M.M., Hirsch, L.J., The ontogeny of partial seizures in infants and young children (2001) Epilepsia, 42 (8), pp. 986-990Fogarasi, A., Jokeit, H., Feveret, E., Jansky, J., Tuxhorn, J., The effect of age on seizure semiology in childhood temporal lobe epilepsy (2002) Epilepsia, 43 (6), pp. 638-643Franzon, R.C., Montenegro, M.A., Guimarães, C.A., Guerreiro, C.A.M., Cendes, F., Guerreiro, M.M., Clinical, electroencephalographic and behavioral features of temporal lobe epilepsy in chidhood (2004) J Child Neurol, 19 (6), pp. 418-423Mimaki, T., Ono, J., Yabuuchi, H., Temporal lobe astrocytoma with infantile spasms (1983) Ann Neurol, 14, pp. 695-696Singer, W., Haller, J., Mills, C., Rabe, E., The value of neuroradiology in infantile spasms (1982) Pediatrics, 100, pp. 47-50Palm, D.G., Brandt, M., Korinthenberg, R., West syndrome and Lennox-Gastaut syndrome in children with porencephalic cysts: Long-term follow-up after neurosurgical treatment (1988) The Lennox-Gastaut syndrome, pp. 419-426. , Niedermeyer E, Degn R, editores, New York: Alan R. Liss;Chugani, H.T., Shields, D., Shewmon, D.A., Olson, D.M., Phelps, M.E., Peacock, W.J., Infantile Spasms: I. PET Identifies Focal Cortical Dysgenesis in Cryptogenic Cases for Surgical Treatment (1990) Ann Neurol, 27, pp. 406-413Chugani, H.T., Infantile Spasms (1995) Neurology, 8, pp. 139-144Miyazaki, M., Hashimoto, T., Fujii, E., Tayama, M., Kuroda, Y., Infantile spasms: Localized cerebral lesions on SPECT (1994) Epilepsia, 35, pp. 988-992Chugani, H.T., Silva, E., Chugani, D.C., Infantile Spasms: III. Prognostic Implications of Bitemporal Hypometabolism on Positron Emission Tomography (1996) Ann Neurol, 39, pp. 643-649Dalla Bernardina, B., Colamaria, V., Capoville, G., Epileptic syndromes and cerebral malformations in infancy: Multicentric study (1984) Boll Lega Ital Epil, 45-46, pp. 65-67Carrazana, E.J., Lombroso, C.T., Mikati, M., Helmers, S., Holmes, G.L., Facilitation of Infantile Spasms by partial seizures (1993) Epilepsia, 34, pp. 686-691Alvarez, L.A., Shinnar, S., Moshe, S.L., Infantile spasms due to unilateral cerebral infarcts (1987) Pediatrics, 79, pp. 1024-102