Galectin-3 is a multifunctional protein highly expressed in thyroid cancer. The galectin-3 gene (LGALS3) has several annotated candidates SNPs, however the relationship between galectin-3 SNPs and specific phenotypic variations relevant to health has not been evaluated. In this study, we investigated SNPs in the galectin-3 gene and a putative association with thyroid tumorigenesis. The presence of LGALS3 SNPs in thyroid carcinoma cell lines (NPA, TPC-1, WRO, ARO), thyroid tissues of 55 patients with multinodular goiter or papillary carcinoma diagnosis and lymphocytes of peripherical blood of 45 healthy individuals was evaluated by sequencing and SSCP. The analysis of LGALS3 coding sequence showed that the T98P site presents a great genotypi...
BACKGROUND: The cancer of the thyroid gland is characterized by its clinical and pathological variet...
Galectin-3 (Gal-3) is an anti-apoptotic molecule of the P-galactoside-binding lectin family. Gal-3 i...
BACKGROUND: Papillary thyroid carcinoma is becoming the common carcinomas among Indian population....
Galectin-3 is a multifunctional protein highly expressed in thyroid cancer. The galectin-3 gene (LGA...
Galectin-3 is a multifunctional protein highly expressed in thyroid cancer. The galectin-3 gene (LGA...
Neste estudo, investigamos o envolvimento de galectina-3 na fisiologia e no câncer de tiróide usando...
Genomic wide association studies and intensive bioinformatic searches of databases have identified ...
BACKGROUND: Galectin-3 (LGALS3) is an important glycoprotein involved in the malignant transformatio...
INTRODUCTION: Galectin family members have been demonstrated to be abnormally expressed in cancer at...
Galectin-3 has been extensively studied as an immunohistochemical marker of thyroid malignancy, and ...
Galectin-3 is involved in thyroid carcinogenesis. The single nucleotide polymorphism (SNP) rs4644 (...
Abstract: Background. Galectin-3 has been recently recog-nized as a promising presurgical marker of ...
In order to supplement the cytopathological assessment of thyroid tumors, there is a need for new ma...
Background: Galectin-3 is an endogenous beta-galactoside binding lectin implicated in neoplastic tra...
OBJECTIVE AND DESIGN: Galectin-3 is a beta-galactoside-binding protein that plays a role in cell adh...
BACKGROUND: The cancer of the thyroid gland is characterized by its clinical and pathological variet...
Galectin-3 (Gal-3) is an anti-apoptotic molecule of the P-galactoside-binding lectin family. Gal-3 i...
BACKGROUND: Papillary thyroid carcinoma is becoming the common carcinomas among Indian population....
Galectin-3 is a multifunctional protein highly expressed in thyroid cancer. The galectin-3 gene (LGA...
Galectin-3 is a multifunctional protein highly expressed in thyroid cancer. The galectin-3 gene (LGA...
Neste estudo, investigamos o envolvimento de galectina-3 na fisiologia e no câncer de tiróide usando...
Genomic wide association studies and intensive bioinformatic searches of databases have identified ...
BACKGROUND: Galectin-3 (LGALS3) is an important glycoprotein involved in the malignant transformatio...
INTRODUCTION: Galectin family members have been demonstrated to be abnormally expressed in cancer at...
Galectin-3 has been extensively studied as an immunohistochemical marker of thyroid malignancy, and ...
Galectin-3 is involved in thyroid carcinogenesis. The single nucleotide polymorphism (SNP) rs4644 (...
Abstract: Background. Galectin-3 has been recently recog-nized as a promising presurgical marker of ...
In order to supplement the cytopathological assessment of thyroid tumors, there is a need for new ma...
Background: Galectin-3 is an endogenous beta-galactoside binding lectin implicated in neoplastic tra...
OBJECTIVE AND DESIGN: Galectin-3 is a beta-galactoside-binding protein that plays a role in cell adh...
BACKGROUND: The cancer of the thyroid gland is characterized by its clinical and pathological variet...
Galectin-3 (Gal-3) is an anti-apoptotic molecule of the P-galactoside-binding lectin family. Gal-3 i...
BACKGROUND: Papillary thyroid carcinoma is becoming the common carcinomas among Indian population....