Add to ORKGThe synthesis and utility of the 3,3-dimethyl-5-substituted-2-pyrrolidinone 'Quat' chiral auxiliary in stereoselective enolate reactions of attached N-acyl side chains combined with the mild and non-racemising conditions required for the ultimate removal of the chiral side chain is described. © 2002 Elsevier Science Ltd. All rights reserved
Sodium and potassium enolates of 1,3-diacylimidazolidin-2-ones undergo clean alkylation reactions wi...
The preparation of a series of chiral 3‐methyl‐3‐substituted‐pyrrolidines/pyrrolidinones starting fr...
A direct and versatile route enabling the regio- and diastereoselective synthesis of 2,5-disubstitut...
The synthesis and utility of the 3,3-dimethyl-5-substituted-2-pyrrolidinone 'Quat' chiral auxiliary ...
The synthesis of a series of chiral auxiliaries, 5-substituted-3,3-dimethyl-2-pyrrolidinones, "quats...
Enolates derived from the N-propionoyl derivative of the "quat" chiral auxiliary (R)-(-)-5-methyl-3,...
A concise approach to cis-2,5-disubstituted pyrrolidines is reported, which relies upon N-tert-butox...
A novel route into chiral amides is achieved through the efficient, non-racemising, cleavage of N-ac...
1189-1193(3R, 1ʹS)-3-[(1ʹ-N-Methylamino)ethyl]pyrrolidine 1, which is an important chiral building b...
4-(Methyl, phenyl, benzyl, and i-propyl)-5,5-dimethyl-oxazolidin-2-ones, readily available from α-am...
The synthesis of a new chiral pyrrolidine has been performed using 2,3-O-isopropylidene-D-erythronol...
Chiral auxiliary (3S)-N,N′-bis(p-methoxybenzyl)-3-iso-propylpiperazine-2,5-dione employs a chiral re...
Key Chiral Auxiliary Applications, Second Edition is a detailed compilation of chiral auxiliary appl...
Methodology for the diastereoselective synthesis of 2,5-disubstituted pyrrolidines by reduction of e...
Polyhydroxylated fragments are ubiquitous in natural products possessing interesting biological prop...
Sodium and potassium enolates of 1,3-diacylimidazolidin-2-ones undergo clean alkylation reactions wi...
The preparation of a series of chiral 3‐methyl‐3‐substituted‐pyrrolidines/pyrrolidinones starting fr...
A direct and versatile route enabling the regio- and diastereoselective synthesis of 2,5-disubstitut...
The synthesis and utility of the 3,3-dimethyl-5-substituted-2-pyrrolidinone 'Quat' chiral auxiliary ...
The synthesis of a series of chiral auxiliaries, 5-substituted-3,3-dimethyl-2-pyrrolidinones, "quats...
Enolates derived from the N-propionoyl derivative of the "quat" chiral auxiliary (R)-(-)-5-methyl-3,...
A concise approach to cis-2,5-disubstituted pyrrolidines is reported, which relies upon N-tert-butox...
A novel route into chiral amides is achieved through the efficient, non-racemising, cleavage of N-ac...
1189-1193(3R, 1ʹS)-3-[(1ʹ-N-Methylamino)ethyl]pyrrolidine 1, which is an important chiral building b...
4-(Methyl, phenyl, benzyl, and i-propyl)-5,5-dimethyl-oxazolidin-2-ones, readily available from α-am...
The synthesis of a new chiral pyrrolidine has been performed using 2,3-O-isopropylidene-D-erythronol...
Chiral auxiliary (3S)-N,N′-bis(p-methoxybenzyl)-3-iso-propylpiperazine-2,5-dione employs a chiral re...
Key Chiral Auxiliary Applications, Second Edition is a detailed compilation of chiral auxiliary appl...
Methodology for the diastereoselective synthesis of 2,5-disubstituted pyrrolidines by reduction of e...
Polyhydroxylated fragments are ubiquitous in natural products possessing interesting biological prop...
Sodium and potassium enolates of 1,3-diacylimidazolidin-2-ones undergo clean alkylation reactions wi...
The preparation of a series of chiral 3‐methyl‐3‐substituted‐pyrrolidines/pyrrolidinones starting fr...
A direct and versatile route enabling the regio- and diastereoselective synthesis of 2,5-disubstitut...