Add to ORKGGaucher, the most prevalent lysosomal disorder, is an autosomal recessive inherited disorder due to a deficiency of glucocerebrosidase. Glucocerebrosidase deficiency leads to the accumulation of glucosylceramide primarily in cells of mononuclear-macrophage lineage. Clinical alterations are visceral, hematological, and skeletal. Bone disorder in Gaucher disease produces defects on bone metabolism and structure and patients suffer from bone pain and crisis. Skeletal problems include osteopenia, osteoporosis, osteolytic lesions, and osteonecrosis. On the other hand a chronic stimulation of the immune system is a well-accepted hallmark in this disease. In this review we summarize the latest findings in the mechanisms leading to the bone patholo...
Gaucher disease (GD) is caused by mutations in the glucosylceramidase β (GBA 1) gene that confer a d...
Gaucher disease (GD) is caused by pathogenic mutations in GBA1, the gene that encodes the lysosomal ...
Gaucher disease is a relatively rare metabolic disease caused by the inherited deficiency of the lys...
Gaucher, the most prevalent lysosomal disorder, is an autosomal recessive inherited disorder due to ...
Gaucher disease is a lysosomal storage disorder caused by deficiency of glucocerebrosidase enzymatic...
Gaucher disease (GD) is caused by mutations in the GBA gene that confer a deficient level of activit...
Gaucher disease (GD) is caused by mutations in the GBA gene that confer a deficient level of activit...
Gaucher disease (GD) is caused by mutations in the glucosylceramidase β (GBA 1) gene that confer a d...
Gaucher disease (GD) is an autosomal recessively inherited lysosomal disorder caused by mutations in...
Gaucher disease (GD) is caused by pathogenic mutations in GBA1, the gene that encodes the lysosomal ...
Gaucher disease (GD) is a rare, genetic lysosomal disorder leading to lipid accumulation and dysfunc...
AbstractGaucher disease (GD) is the most frequently encountered lysosomal storage disease caused by ...
Gaucher disease is a rare autosomal recessive disorder of glycosphingolipid metabolism resulting fro...
Gaucher disease (GD) is the most frequently encountered lysosomal storage disease caused by inborn d...
Gaucher disease, the most common lysosomal storage disorder, is caused by β-glucocerebrosidase defic...
Gaucher disease (GD) is caused by mutations in the glucosylceramidase β (GBA 1) gene that confer a d...
Gaucher disease (GD) is caused by pathogenic mutations in GBA1, the gene that encodes the lysosomal ...
Gaucher disease is a relatively rare metabolic disease caused by the inherited deficiency of the lys...
Gaucher, the most prevalent lysosomal disorder, is an autosomal recessive inherited disorder due to ...
Gaucher disease is a lysosomal storage disorder caused by deficiency of glucocerebrosidase enzymatic...
Gaucher disease (GD) is caused by mutations in the GBA gene that confer a deficient level of activit...
Gaucher disease (GD) is caused by mutations in the GBA gene that confer a deficient level of activit...
Gaucher disease (GD) is caused by mutations in the glucosylceramidase β (GBA 1) gene that confer a d...
Gaucher disease (GD) is an autosomal recessively inherited lysosomal disorder caused by mutations in...
Gaucher disease (GD) is caused by pathogenic mutations in GBA1, the gene that encodes the lysosomal ...
Gaucher disease (GD) is a rare, genetic lysosomal disorder leading to lipid accumulation and dysfunc...
AbstractGaucher disease (GD) is the most frequently encountered lysosomal storage disease caused by ...
Gaucher disease is a rare autosomal recessive disorder of glycosphingolipid metabolism resulting fro...
Gaucher disease (GD) is the most frequently encountered lysosomal storage disease caused by inborn d...
Gaucher disease, the most common lysosomal storage disorder, is caused by β-glucocerebrosidase defic...
Gaucher disease (GD) is caused by mutations in the glucosylceramidase β (GBA 1) gene that confer a d...
Gaucher disease (GD) is caused by pathogenic mutations in GBA1, the gene that encodes the lysosomal ...
Gaucher disease is a relatively rare metabolic disease caused by the inherited deficiency of the lys...