International audienceCONTEXT:Few large studies have been conducted to assess the relationship between circulating IGF and late-life cognition.OBJECTIVE: The aim of the study was to assess the relationship between IGF-I and IGF binding protein-3 (IGFBP-3) serum levels and cognitive impairment, including Alzheimer's disease (AD).METHODS: In this multicentric cross-sectional study, 694 elderly subjects (218 men, 476 women; 78.6 ± 6.7 yr old) were included; 481 had memory complaints and were diagnosed, after comprehensive cognitive assessment, with AD (n = 224) or mild cognitive impairment (MCI) (n = 257). The control group was comprised of 213 subjects without memory complaint and with normal cognition (recruited among patients' caregivers). ...
BACKGROUND: The Insulin-like Growth Factor (IGF)-related system is implicated in neuroregeneration a...
Context—Both IGF-1 and cognition decrease with age. IGF-1 is positively associated with cognitive fu...
Background: Insulin-like growth factor (IGF)-1 has been implicated in the pathogenesis of Alzheimer'...
International audienceCONTEXT:Few large studies have been conducted to assess the relationship betwe...
International audienceBackground: The relationship between the insulin-like growth factor-I (IGF-I) ...
OBJECTIVE: To relate serum insulin-like growth factor-1 (IGF-1) to risk of Alzheimer disease (AD) de...
Background: Although insulin-like growth factor-I (IGF-I) is of importance for the adult function of...
OBJECTIVE: To determine the association between plasma insulin-like growth factor binding protein 2 ...
The objective of this study was to investigate the longitudinal relation between the insulin-...
Background: The increasing incidence of cognitive impairment and dementia in an aging population pos...
Background: Alterations in insulin-like growth factor I (IGF-I) signaling have been associated with ...
Context: Increasing evidences from experimental and human studies suggest that the activity of the g...
BACKGROUND: The increasing incidence of cognitive impairment and dementia in an aging population pos...
International audienceBACKGROUND: Insulin-like growth factor-I (IGF-I) serum level decreases with ag...
Background: Alterations in insulin-like growth factor I (IGF-I) signaling have been associated with ...
BACKGROUND: The Insulin-like Growth Factor (IGF)-related system is implicated in neuroregeneration a...
Context—Both IGF-1 and cognition decrease with age. IGF-1 is positively associated with cognitive fu...
Background: Insulin-like growth factor (IGF)-1 has been implicated in the pathogenesis of Alzheimer'...
International audienceCONTEXT:Few large studies have been conducted to assess the relationship betwe...
International audienceBackground: The relationship between the insulin-like growth factor-I (IGF-I) ...
OBJECTIVE: To relate serum insulin-like growth factor-1 (IGF-1) to risk of Alzheimer disease (AD) de...
Background: Although insulin-like growth factor-I (IGF-I) is of importance for the adult function of...
OBJECTIVE: To determine the association between plasma insulin-like growth factor binding protein 2 ...
The objective of this study was to investigate the longitudinal relation between the insulin-...
Background: The increasing incidence of cognitive impairment and dementia in an aging population pos...
Background: Alterations in insulin-like growth factor I (IGF-I) signaling have been associated with ...
Context: Increasing evidences from experimental and human studies suggest that the activity of the g...
BACKGROUND: The increasing incidence of cognitive impairment and dementia in an aging population pos...
International audienceBACKGROUND: Insulin-like growth factor-I (IGF-I) serum level decreases with ag...
Background: Alterations in insulin-like growth factor I (IGF-I) signaling have been associated with ...
BACKGROUND: The Insulin-like Growth Factor (IGF)-related system is implicated in neuroregeneration a...
Context—Both IGF-1 and cognition decrease with age. IGF-1 is positively associated with cognitive fu...
Background: Insulin-like growth factor (IGF)-1 has been implicated in the pathogenesis of Alzheimer'...