International audienceContext. Complex organic molecules (COMs) have been detected in a few Class 0 protostars but their origin is not well understood. While the usual picture of a hot corino explains their presence as resulting from the heating of the inner envelope by the nascent protostar, shocks in the outflow, disk wind, the presence of a flared disk, or the interaction region between envelope and disk at the centrifugal barrier have also been claimed to enhance the abundance of COMs.Aims. Going beyond studies of individual objects, we want to investigate the origin of COMs in young protostars on a statistical basis.Methods. We use the CALYPSO survey performed with the Plateau de Bure Interferometer of the Institut de Radioastronomie M...