Homozygosity for HLA-A3 and the microsatellite markers D6S265 allele 1 and D6S105 allele 8 is associated with a high relative risk for genetic haemochromatosis — indeed we and others have suggested that a haplotype including D6S265-1, HLA-A3 and D6S105-8 is specific for haemochromatosis. To determine the frequency of this haplotype and examine its specificity for haemochromatosis we have analysed data from 7820 blood donors from South Wales. The frequency of homozygosity for D6S265-1, HLA-A3 and D6S105-8 was 1 in 280. Calculations based on the prevalence of haemochromatosis suggest that about 50% of chromosomes carrying D6S265-1:HLA-A3:D6S105-8 also carry the haemochromatosis gene. This information is of value for assessing the risk that th...
Abstract Background We wanted to quantify HLA-A and -B allele and haplotype frequencies in Alabama h...
BACKGROUND The diagnosis of genetic haemochromatosis (GH) before iron overload has developed is diff...
Hereditary Hemochromatosis (HH) is a recessively inherited disorder of iron overload occurring commo...
Homozygosity for HLA-A3 and the microsatellite markers D6S265 allele 1 and D6S105 allele 8 is associ...
Hereditary haemochromatosis is an HLA-linked, recessive disorder with HLA-A3 a strong marker for the...
Haemochromatosis (GH) is an autosomal recessive disorder in which increased iron absorption causes i...
The haemochromatosis gene (HFE) is linked to both HLA-A and D6S105 on the short arm of chromosome 6 ...
The HLA-A3 homozygous genotype frequency has been determined in healthy individuals using the HLA-A ...
Haemochromatosis is the most common single gene disorder to afflict North- West European populations...
Hereditary Hemochromatosis (HH) is a recessively inherited disorder of iron overload occurring commo...
Genetic hemochromatosis is one of the most common inherited disoders in Caucasian populations. The d...
The hemochromatosis gene, HFE, is located on chromosome 6 in close proximity to the HLA-A locus. Mos...
Hemochromatosis (HC) is an inherited disorder of iron metabolism and is frequently seen in Caucasian...
The frequencies of different HLA-A and -B alleles in 77 Australian patients with hemochromatosis hav...
This study looks at expression of genetic hemochromatosis in the homozygous and heterozygous states....
Abstract Background We wanted to quantify HLA-A and -B allele and haplotype frequencies in Alabama h...
BACKGROUND The diagnosis of genetic haemochromatosis (GH) before iron overload has developed is diff...
Hereditary Hemochromatosis (HH) is a recessively inherited disorder of iron overload occurring commo...
Homozygosity for HLA-A3 and the microsatellite markers D6S265 allele 1 and D6S105 allele 8 is associ...
Hereditary haemochromatosis is an HLA-linked, recessive disorder with HLA-A3 a strong marker for the...
Haemochromatosis (GH) is an autosomal recessive disorder in which increased iron absorption causes i...
The haemochromatosis gene (HFE) is linked to both HLA-A and D6S105 on the short arm of chromosome 6 ...
The HLA-A3 homozygous genotype frequency has been determined in healthy individuals using the HLA-A ...
Haemochromatosis is the most common single gene disorder to afflict North- West European populations...
Hereditary Hemochromatosis (HH) is a recessively inherited disorder of iron overload occurring commo...
Genetic hemochromatosis is one of the most common inherited disoders in Caucasian populations. The d...
The hemochromatosis gene, HFE, is located on chromosome 6 in close proximity to the HLA-A locus. Mos...
Hemochromatosis (HC) is an inherited disorder of iron metabolism and is frequently seen in Caucasian...
The frequencies of different HLA-A and -B alleles in 77 Australian patients with hemochromatosis hav...
This study looks at expression of genetic hemochromatosis in the homozygous and heterozygous states....
Abstract Background We wanted to quantify HLA-A and -B allele and haplotype frequencies in Alabama h...
BACKGROUND The diagnosis of genetic haemochromatosis (GH) before iron overload has developed is diff...
Hereditary Hemochromatosis (HH) is a recessively inherited disorder of iron overload occurring commo...