In recent years, there has been a renewed interest in the role of dietary fibre in obesity management. Much of this interest stems from animal and human studies which suggest that an increased intake of fermentable fibre can suppress appetite and improve weight management. A growing number of reports have demonstrated that the principal products of colonic fermentation of dietary fibre, SCFA, contribute to energy homeostasis via effects on multiple cellular metabolic pathways and receptor-mediated mechanisms. In particular, over the past decade it has been identified that a widespread receptor system exists for SCFA. These G-protein-coupled receptors, free fatty acid receptor (FFAR) 2 and FFAR3 are expressed in numerous tissue sites, inclu...
Background and Objectives:The gut hormones PYY and GLP-1 acutely suppress appetite. The short chain ...
Intake, absorption and synthesis of fatty acids, including those produced by the intestinal microbio...
Introduction: Ketogenic diets (KDs) have the ability to suppress the increase in appetite otherwise ...
The recently discovered SCFA-activated G-coupled protein receptors FFA receptor 2 and FFA receptor 3...
The current obesity epidemic poses a major challenge to public health. Apart from bariatric surgery,...
Over the last 20 years there has been an increasing interest in the influence of the gastrointestina...
Short-chain fatty acids (SCFA) are produced by colonic microbiota, mostly from dietary fiber. Mice s...
Humans are living in an increasingly 'obesogenic' environment with easily accessed, energy dense foo...
This thesis investigates the ability of fermentable carbohydrates to stimulate anorectic gut hormone...
A number of animal and human investigations have demonstrated that dietary supplementation with non-...
The gastrointestinal (GI) tract is separated from the body’s internal environment by a single layer ...
Imbalances in energy regulation lead to metabolic disorders such as obesity and diabetes. Diet plays...
Imbalances in energy regulation lead to metabolic disorders such as obesity and diabetes. Diet plays...
Study of the interactions between the gut microbiota and brain-gut axis represents a very appealing ...
Obesity is caused by prolonged energy surplus. Current anti-obesity medications are mostly centraliz...
Background and Objectives:The gut hormones PYY and GLP-1 acutely suppress appetite. The short chain ...
Intake, absorption and synthesis of fatty acids, including those produced by the intestinal microbio...
Introduction: Ketogenic diets (KDs) have the ability to suppress the increase in appetite otherwise ...
The recently discovered SCFA-activated G-coupled protein receptors FFA receptor 2 and FFA receptor 3...
The current obesity epidemic poses a major challenge to public health. Apart from bariatric surgery,...
Over the last 20 years there has been an increasing interest in the influence of the gastrointestina...
Short-chain fatty acids (SCFA) are produced by colonic microbiota, mostly from dietary fiber. Mice s...
Humans are living in an increasingly 'obesogenic' environment with easily accessed, energy dense foo...
This thesis investigates the ability of fermentable carbohydrates to stimulate anorectic gut hormone...
A number of animal and human investigations have demonstrated that dietary supplementation with non-...
The gastrointestinal (GI) tract is separated from the body’s internal environment by a single layer ...
Imbalances in energy regulation lead to metabolic disorders such as obesity and diabetes. Diet plays...
Imbalances in energy regulation lead to metabolic disorders such as obesity and diabetes. Diet plays...
Study of the interactions between the gut microbiota and brain-gut axis represents a very appealing ...
Obesity is caused by prolonged energy surplus. Current anti-obesity medications are mostly centraliz...
Background and Objectives:The gut hormones PYY and GLP-1 acutely suppress appetite. The short chain ...
Intake, absorption and synthesis of fatty acids, including those produced by the intestinal microbio...
Introduction: Ketogenic diets (KDs) have the ability to suppress the increase in appetite otherwise ...