Hetero‐Oligomerization of Chemokine Receptors

Although traditionally assumed to be monomeric signaling units, G[hyphen (true graphic)]protein-coupled receptors (GPCRs) have been shown to exist as dimers/oligomers. Many chemokine receptors have been demonstrated to form homo[hyphen (true graphic)]oligomers, and hetero[hyphen (true graphic)]oligomerization between both pairs of chemokine receptors and chemokine receptors and other GPCRs has also been demonstrated. This chapter highlights some of the most common techniques used to investigate chemokine receptor oligomerizatio