Loss of the p53 tumor suppressor pathway contributes to the development of most human cancers. p53 is a nuclear protein that functions as a regulator of transcription. Significant advances have been made recently in our understanding of how p53 function is regulated and the mechanisms by which p53 mediates its effects
International audiencep53, p63 and p73 are members of the p53 gene family involved in development, d...
The tumor protein TP53 gene, encoding the cellular tumor antigen p53, is the single most frequently ...
Few proteins are more studied than the p53 tumour suppressor, but what have we learned from these st...
The p53 protein is an important tumour suppressor that is inactivated in many human cancers. Underst...
p53, a homo-tetrameric protein found in mammalian cells, derives its name from the fact that it sett...
p53 has been studied intensively as a major tumour suppressor that detects oncogenic events in cance...
DNA damage triggers a checkpoint response that involves a myriad of cellular responses including cel...
The p53 protein is a transcription factor known as the "guardian of the genome" because of its criti...
p53, p63 and p73 are members of the p53 gene family involved in development, differentiation and res...
Alterations in the expression of and response to growth factors is one of the biological characteris...
The mutation of TP53 gene affects half of all human cancers, resulting in impairment of the regulati...
The TP53 tumor suppressor is the most frequently mutated gene in human cancer. p53 suppresses tumori...
As a key transcription factor, the evolutionarily conserved tumor suppressor p53 (encoded by TP53) p...
International audiencep53, p63 and p73 are members of the p53 gene family involved in development, d...
The tumor protein TP53 gene, encoding the cellular tumor antigen p53, is the single most frequently ...
Few proteins are more studied than the p53 tumour suppressor, but what have we learned from these st...
The p53 protein is an important tumour suppressor that is inactivated in many human cancers. Underst...
p53, a homo-tetrameric protein found in mammalian cells, derives its name from the fact that it sett...
p53 has been studied intensively as a major tumour suppressor that detects oncogenic events in cance...
DNA damage triggers a checkpoint response that involves a myriad of cellular responses including cel...
The p53 protein is a transcription factor known as the "guardian of the genome" because of its criti...
p53, p63 and p73 are members of the p53 gene family involved in development, differentiation and res...
Alterations in the expression of and response to growth factors is one of the biological characteris...
The mutation of TP53 gene affects half of all human cancers, resulting in impairment of the regulati...
The TP53 tumor suppressor is the most frequently mutated gene in human cancer. p53 suppresses tumori...
As a key transcription factor, the evolutionarily conserved tumor suppressor p53 (encoded by TP53) p...
International audiencep53, p63 and p73 are members of the p53 gene family involved in development, d...
The tumor protein TP53 gene, encoding the cellular tumor antigen p53, is the single most frequently ...
Few proteins are more studied than the p53 tumour suppressor, but what have we learned from these st...
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