POLA PENGOBATAN DAN LUARAN KLINIS PADA TERAPI ERADIKASI PASIEN TERINFEKSI HELICOBACTER PYLORI DI YOGYAKARTA

The prevalence of Helicobacter pylori (H. pylori) varies around the world and depends on the standard of living in their respective areas. In handling it, there are several regimens of H. pylorieradication therapy that can affect the clinical outcome of each patient. This study aims to investigate the treatment pathways and clinical outcome of patients. This study was a multicenter study conducted in three hospitals with observational analitic design of the cross sectional method, data collection was done retrospectively using secondary data from 1 January 2009 to 31 May 2014. The number of patients who meet the inclusion and exclusion criteria were 47 patients. The way assessment of clinical outcomes by looking at the initial complaint that patients perceived grievances felt compared with patients after therapy. General characteristics of the patients were male (53,2%), aged under 59 years (68,1%), askes participants (57,4%), senior high school education (29,8%), and the work of civil servants (23,4%). A total of 37 patients (78,7%) received therapy with antibiotics, and 10 patients (21,3%) was not taken antibiotics. The combination of amoxicillin-clarithromycin is the most widely used combination (72,3%). Complaints have felt patients were nausea (48,93%), abdominal pain (48,93%), melena (40,42%), vomite (31,91%), epigastric pain (31,91%), diarrhea (19,14%), hematemesis (17,02%) and lack ofappetite (17.02%). There is a significant difference in the improvement of clinical outcomes between patients who received antibiotics to patients who did not receive antibiotics (p = 0,04