HAEMATOLOGY STUDY AND HISTOPATHOLOGICAL CHANGES OF JEJUNUM, LIVER AND HEART IN DOGS INFECTED BY CANINE PARVOVIRUS

Numerous studies have proved that parvovirus can be diagnosed using varies different methods but not haematology as its definitive diagnosis. This research is done specifically to know if diagnosing Canine Parvovirus histopathologically and haematologically is enough to be a definitive diagnosis. The aim of this study is to identify and comparing the samples that were collected from puppies that were infected by Canine Parvovirus, between the conventional histopathological methods. It also functions to further identify the changes that occur in a canine parvovirus patient haematologically. This is a descriptive study which 5 patients were suspected for parvovirus and was admitted in RSH Soeparwi and Kuningan, Yogyakarta in the month of August 2012. The patients were selected in a non probability or random consecutive sampling method.The most significant pathological changes of Canine Parvovirus are gastroenteritis and myocarditis. From this study, it was found that all the dogs were having hemolytic anemia. Histopathologically, diffuse damage to the crypt epithelium and severe loss of villous epithelium and necrosis of the villi causing blunting and sloughing are observed in the intestine. Kidney and liver are damaged due to severe septicaemia in the case of parvovirus. Hematologically, neutropenia, lymphocytosis, anemia and thrombocytopenia in the dogs should indicate Canine Parvovirus. However, these diagnostic test are not enough to conclude that the dog is suffering from Canine Parvovirus. PCR or ELISA can be done to make a more specific diagnosis