KEJANG BERULANG DAN STATUS EPILEPTIKUS PADA ENSEFALITIS SEBAGAI FAKTOR RISIKO EPILEPSI PASCAENSEFALITIS

Background: Postencephalitic epilepsy is not a rare complication of acute encephalitis that require longlife treatment and affect quality of life. There are some risk factors for development of postencephalitic epilepsy, the most important one is seizure during acute encephalitis. Objective: To determine the risk of having postencephalitic epilepsy based on the presence of recurrent seizure and status epilepticus during acute phase of encephalitis. Methods: A case-control study was conducted. 26 patients with postencephalitic epilepsy were enrolled as case group, and 27 patients postencephalitic with other sequele or no sequele as control group. The clinical data during acute phase of encephalitis include recurrent seizure and status epilepticus were derived from data of medical records of encephalitis patient in Dr. Sardjito hospital, Yogyakarta. Statistical analysis was done by using chi-square. Logistic regression analysis was done to determine the role of risk factors. Results: Total 53 children were enrolled. Of these, 41 (77,4 %) 6 months-5 years old and 12 (22,6 %) 6-18 years old, 32 (60,4 %) male and 21 (39,6 %) female. The children with recurrent seizure during acute encephalitis had increased risk of developing postencephalitic epilepsy (OR 3,