VALIDATION OF VOLTAMMETRY METHOD FOR TRACE METALS ANALYSIS IN BIOLOGICAL SAMPLES

Validation of voltammetric method for, Cd, Pb, Zn, Ni, Co, Al and Fe determination in biological samples, has been done using standard reference materials. Anodic stripping voltammetry has been used on Cu, Cd, Pb and Zn determination. Mean while adsorptive cathodic stripping voltammetry, in dimethylglioxime complexing agent has been used for Ni and Co determination, and finally adsorptive cathodic stripping voltammetry in solochrome violete complexing agent used on Al and Fe determination. The validation method consist of a linearity of standard calibration, trueness and precision. The validation carried out by using standard reference materials of NIST SRM 1566 b Oyster Tissue and CRM NIES No. 9 Sargasso. Sample digestion has been done by using the micro wave digester apparatus. It has been shown that the standard curves linearity for all ions were good enough. The ions determinations in a material standard have a recovery of about 92.2 -104.3 %. From the &ldqu