Jumlah Limfosit Absolut Dan Relatif Pada Infeksi Dengue

'Fakultas Kedokteran Universitas Gadjah Mada, Yogyakarta 2Bagian Ilmu Kesehatan Anak, Fakultas Kedokteran Universitas Gadjah Mada/ Rumah Sakit Dr. Sardjito, Yogyakarta ABSTRACT Bambang Ardianto, Sumadiono, Sutaryo - Absolute and relative lymphocyte counts in dengue infection Background: Dengue infection is one of Indonesia's health problems. Lymphocytes are thought to be involved in dengue pathogenesis. Objectives: To determine whether there were any differences on absolute and relative lymphocyte counts between dengue and non-dengue febrile patients and among dengue fever (DF), dengue hemorrhagic fever without shock (DHF�, dengue shock syndrome (DSS), and non-dengue (ND) patients. Methods: A cross-sectional study was conducted on dengue and non-dengue patients hospitalized at "Empat Lima" Hospital, Yogyakarta, during the period of November 23, 2001-January 22, 2002. The diagnosis of dengue infection was confirmed by HI test. Absolute and relative lymphocyte counts were obtained from serial peripheral blood films stained with Giemsa's staining. Results: Thirty-eight DF, 10 DHF, 16 DSS, and 86 ND patients were involved in this study. Absolute and relative counts of each degree were compared each other from the third day until the eighth day after the onset of fever. Absolute lymphocyte counts of dengue patients were higher than those of non-dengue patients on day 5 (p=0.047) and 6 (p =0.022). Absolute lymphocyte counts of DHF patients were higher than those of DF, DSS, and ND patients on day 5 (DF vs. DHF, p =0.00