Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes

This review highlights the biological importance of many polysubstituted nitro-prolines and -pyrrolidines. Their preparation using asymmetric 1,3-dipolar cycloadditions of azomethine ylides with nitroalkenes using diastereoselective and enantioselective strategies is described remarking the scope and main features of each one.This work has been supported by the Spanish Ministerio de Economía y Competitividad (MINECO) (Consolider INGENIO 2010 CSD2007-00006, CTQ2010-20387), FEDER, Generalitat Valenciana (PROMETEO/2009/039), and by the University of Alicante