This diploma thesis focuses on the selection process of the enterprise information system in the enterprise. The general investment process and vendor selection process are described in the theoretical part. This part also includes the analysis of the specifics and differences of the selection process of the information system and recommended methodology for public tender. The optimized selection process of enterprise information system is designed on the basis of specialized literature and found deficiencies. The applicability of the proposed process in practice is assessed through comparison with a case study of a successful selection of an information system in the final part of the thesis. The design can be considered usable in practice...