FORMULASI DAN UJI KRIM EKSTRAK UMBI SINGKONG (Manihot esculenta) TERHADAP LUKA BAKAR PADA KELINCI (Oryctolagus cuniculus)

Crops Cassava (Manihot esculenta) contains carbohydrates, phosphorus, calcium, vitaminC, protein, iron and vitamin B1 can provide a healing effect on wounds. The content contained incassava able to give effect to the skin re-epithelialization of damaged tissues due to burns. Thisstudy aims to determine the effectiveness of the test extract tubers Cassava (Manihot esculenta) inthe dosage form of a cream with the concentration level of 2%, 4%, and 8% for burn woundhealing in rabbits (Oryctolagus cuniculus). Making cream formulation using cassava tuber extractoil phase in water and used as test animals 10 rabbits, divided into 5 treatment groups, namely, testthe cream treatment group, negative control group (basic cream) and a positive control group(Bioplacenton). Burns in the back with a diameter of 1.5 cm were treated and observed the healingeffects for 7 days. The results showed that from day-1 to day-7 observations burns suffereddiminution in diameter. It was concluded that the concentration of 2% cassava extract cream hashealing effect and increasing the concentration of 4% and 8% contained showed more effectiveand speed up the healing process.Keywords: cream, extract, cassava tubers, healing burns, rabbi