This study aims to relate the intra-seasonal rainfall variability over the Amazon basin to atmospheric circulation patterns (CPs), with particular attention to extreme rainfall events in the Amazon–Andes region. The CPs summarize the intra-seasonal variability of atmospheric circulation and are defined using daily low-level winds from the ERA-Interim (1.5° × 1.5°) reanalysis for the 1979–2014 period. Furthermore, observational data of precipitation and high-resolution TRMM 3B42 (∼25 km), 2A25 PR (∼5 km) and CHIRPS (∼5 km) data products are related to the CPs throughout the Amazon basin. Nine CPs are determined using a hybrid method that combines a neural network technique (self-organizing maps, SOM) and hierarchical ascendant classification...