Exploration of the Effect of Tobacco Smoking on Metabolic Measures in Young People Living with HIV

Mark L. Rubinstein
D. Robert Harris
Bret J. Rudy
Bill G. Kapogiannis
Grace M. Aldrovandi
Kathleen Mulligan

Open link

Publication date

January 2014

DOI

10.1155/2014/740545

Publisher

Hindawi Limited

ISSN

2090-1240

Journal

AIDS Research and Treatment

Citation count (estimate)

Abstract

We conducted cross-sectional, multicenter studies in HIV-positive young women and men to assess metabolic and morphologic complications from tobacco smoking in 372 behaviorally infected HIV-positive youth, aged 14–25 years. Measurements included self-reported tobacco use, fasting lipids, glucose, fat distribution, and bone mineral density (BMD; dual-energy X-ray absorptiometry scans). Overall, 144 (38.7%) self-reported smoking tobacco and 69 (47.9%) of these reported smoking greater than five cigarettes per day. Smokers versus nonsmokers had lower mean total cholesterol (146.0 versus 156.1 mg/dL; P<0.01) and lower mean total body fat percent (24.1% versus 27.2%, P=0.03). There was no difference between smokers and nonsmokers in fasting gluc...