In order to develop a universal account of enduring, immanent human interests upon which to mount a case against cultural sources of injury, it is necessary to overcome a series of ‘relativist’ claims regarding the nature of the human condition. My aim in this chapter is to unpack these claims and, by examining elements of the work of John Gray, to suggest means by which to overcome them. To do this, I outline, first, the empirical case against universalism and, second, the epistemological and methodological basis of the anti-universalist paradigms — social constructivism. I then identify three different, and to varying degrees incompatible, schematic claims. The first, anti-foundationalist, schema holds that there can be no objective basis...