Raw data files supporting the manuscript 'Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity'. Including raw HDX-MS data for up to 6 replicates for two labelling conditions (with and without Ca2+) and MS/MS mapping files. Raw nano-ESI-EM and nano-ESI-IM-MS data of three replicates with and without Ca2+. Raw NMR data files for three aSyn varients with and without Ca2+. Raw ThT-based aggregation kinetic data. Additional AFM files. Primer sequences
The protein alpha synuclein is the primary component in the amyloid fibrils that form the pathogenic...
Familial mutations in alpha-synuclein affect the immediate chemical environment of the protein's bac...
Introduction The pathogenicity at differing points along the aggregation pathway of many fibril-form...
As an intrinsically disordered protein, monomeric alpha-synuclein (aSyn) occupies a large conformati...
As an intrinsically disordered protein, monomeric alpha-synuclein (aSyn) occupies a large conformati...
Raw data for the Nature Structural Molecular Biology paper "A short motif in the N-terminal region o...
Alpha-synuclein (αS) and beta-synuclein (βS) are small pre-synaptic, neuronal proteins, which have h...
The misfolding and aggregation of alpha-synuclein (aSyn) are thought to be central events in synucle...
The experimental data in this dataset is the basis of the article entitled "Elevated concentrations ...
ABSTRACT: α-Synuclein is an intrinsically disordered protein whose aggregation is implicated in Park...
The intrinsically disordered protein (IDP) alpha-synuclein (αSyn) is known to be involved in neurode...
The kinetics of aggregation of alpha-synuclein are usually studied by turbidity or Thio-T fluorescen...
Alpha-synuclein (α-SYN) aggregates represent a key feature of Parkinson's disease, but the exact rel...
This data set includes the raw western blot data for main and supplemental figures to accompany Fred...
Data, computational software, and supplemental movies generated in the study: "Quantitative Characte...
The protein alpha synuclein is the primary component in the amyloid fibrils that form the pathogenic...
Familial mutations in alpha-synuclein affect the immediate chemical environment of the protein's bac...
Introduction The pathogenicity at differing points along the aggregation pathway of many fibril-form...
As an intrinsically disordered protein, monomeric alpha-synuclein (aSyn) occupies a large conformati...
As an intrinsically disordered protein, monomeric alpha-synuclein (aSyn) occupies a large conformati...
Raw data for the Nature Structural Molecular Biology paper "A short motif in the N-terminal region o...
Alpha-synuclein (αS) and beta-synuclein (βS) are small pre-synaptic, neuronal proteins, which have h...
The misfolding and aggregation of alpha-synuclein (aSyn) are thought to be central events in synucle...
The experimental data in this dataset is the basis of the article entitled "Elevated concentrations ...
ABSTRACT: α-Synuclein is an intrinsically disordered protein whose aggregation is implicated in Park...
The intrinsically disordered protein (IDP) alpha-synuclein (αSyn) is known to be involved in neurode...
The kinetics of aggregation of alpha-synuclein are usually studied by turbidity or Thio-T fluorescen...
Alpha-synuclein (α-SYN) aggregates represent a key feature of Parkinson's disease, but the exact rel...
This data set includes the raw western blot data for main and supplemental figures to accompany Fred...
Data, computational software, and supplemental movies generated in the study: "Quantitative Characte...
The protein alpha synuclein is the primary component in the amyloid fibrils that form the pathogenic...
Familial mutations in alpha-synuclein affect the immediate chemical environment of the protein's bac...
Introduction The pathogenicity at differing points along the aggregation pathway of many fibril-form...