Add to ORKGThe present thesis describes the identification and characterization of sequence variants in the cardiac ion channel genes KCNH2 and SCN5A. The variants were found in sudden cardiac death victims, in patients with ion channel diseases and in their family members. The results support the growing awareness that carriership of a single mutation often fails to predict the clinical phenotype and that additional genetic modifications may influence the clinical manifestation of the disease
Brugada syndrome (BrS) is one of the ion channelopathies associated with sudden cardiac death (SCD)....
ObjectivesThe aim of this study was to discern the role of the cardiac voltage-gated sodium ion chan...
Introduction. Atrial fibrillation (AF) is the most common sustained arrhythmia, and it results in si...
The present thesis describes the identification and characterization of sequence variants in the car...
Sequence variants in the ion channel genes KCNH2 and SCN5A may cause the cardiac disorder long QT sy...
Sudden arrhythmic death syndrome (SADS) in young individuals is a devastating and tragic event often...
AbstractIntroductionStrong evidence suggests that sudden cardiac death (SCD) is genetically determin...
Sudden arrhythmic death syndrome (SADS) in young individuals is a devastating and tragic event often...
Congenital long-QT syndrome (LQTS) is a cardiac channelopathy caused by mutations in genes that enco...
Sudden cardiac death (SCD) describes a natural and unexpected death from cardiac causes occurring wi...
Abstract Sudden cardiac death (SCD) describes a natural and unexpected death from cardiac causes occ...
The cause of sudden death in young people remains unknown in up to 50% of postmortem cases. Mutation...
Background. Congenital heart block is characterized by blockage of electrical impulses from the atri...
BackgroundThe cardiac sodium channel SCN5A regulates atrioventricular and ventricular conduction. Ge...
Background Although stillbirth is a significant health problem worldwide, the definitive cause of de...
Brugada syndrome (BrS) is one of the ion channelopathies associated with sudden cardiac death (SCD)....
ObjectivesThe aim of this study was to discern the role of the cardiac voltage-gated sodium ion chan...
Introduction. Atrial fibrillation (AF) is the most common sustained arrhythmia, and it results in si...
The present thesis describes the identification and characterization of sequence variants in the car...
Sequence variants in the ion channel genes KCNH2 and SCN5A may cause the cardiac disorder long QT sy...
Sudden arrhythmic death syndrome (SADS) in young individuals is a devastating and tragic event often...
AbstractIntroductionStrong evidence suggests that sudden cardiac death (SCD) is genetically determin...
Sudden arrhythmic death syndrome (SADS) in young individuals is a devastating and tragic event often...
Congenital long-QT syndrome (LQTS) is a cardiac channelopathy caused by mutations in genes that enco...
Sudden cardiac death (SCD) describes a natural and unexpected death from cardiac causes occurring wi...
Abstract Sudden cardiac death (SCD) describes a natural and unexpected death from cardiac causes occ...
The cause of sudden death in young people remains unknown in up to 50% of postmortem cases. Mutation...
Background. Congenital heart block is characterized by blockage of electrical impulses from the atri...
BackgroundThe cardiac sodium channel SCN5A regulates atrioventricular and ventricular conduction. Ge...
Background Although stillbirth is a significant health problem worldwide, the definitive cause of de...
Brugada syndrome (BrS) is one of the ion channelopathies associated with sudden cardiac death (SCD)....
ObjectivesThe aim of this study was to discern the role of the cardiac voltage-gated sodium ion chan...
Introduction. Atrial fibrillation (AF) is the most common sustained arrhythmia, and it results in si...