Add to ORKGRiboswitches are natural RNA-based genetic switches that sense small-molecule metabolites and regulate in response the expression of the corresponding metabolic genes. Within the last years, several engineered riboswitches have been developed that act on various stages of gene expression. These switches can be engineered to respond to any ligand of choice and are therefore of great interest for synthetic biology. In this review, we present an overview of engineered riboswitches and discuss their application in conditional gene expression systems. We will provide structural and mechanistic insights and point out problems and recent trends in the development of engineered riboswitches
Riboswitches are cis-acting regulatory elements broadly distributed in bacterial mRNAs that control ...
Re-engineered riboswitches that no longer respond to cellular metabolites, but that instead can be c...
<div><p>Riboswitches are RNA-based regulators of gene expression composed of a ligand-sensing aptame...
AbstractRiboswitches are natural RNA-based genetic switches that sense small-molecule metabolites an...
During the last years the great importance of RNA for regulating gene expression in all organisms ha...
The first conditional gene expression system which employed a small molecule binding aptamer was dev...
RNA utilizes many different mechanisms to control gene expression. Among the regulatory elements tha...
Several techniques originating from synthetic biology have a big impact on the field of metabolic en...
SummaryRiboswitches are RNA-based genetic control elements that regulate gene expression in a ligand...
The ability to independently control the expression of multiple genes by addition of distinct small-...
Synthetic biology uses our understanding of biological systems to develop innovative solutions for c...
RNA is a versatile biomolecule capable of transferring information, taking on distinct three-dimensi...
During the last years, the important role RNA plays for regulating gene expression in all organisms ...
Riboswitches are segments of pre-mRNAs and mRNAs, present in their UTRs or introns, which are able t...
Riboswitches are common gene regulatory units mostly found in bacteria that are capable of altering ...
Riboswitches are cis-acting regulatory elements broadly distributed in bacterial mRNAs that control ...
Re-engineered riboswitches that no longer respond to cellular metabolites, but that instead can be c...
<div><p>Riboswitches are RNA-based regulators of gene expression composed of a ligand-sensing aptame...
AbstractRiboswitches are natural RNA-based genetic switches that sense small-molecule metabolites an...
During the last years the great importance of RNA for regulating gene expression in all organisms ha...
The first conditional gene expression system which employed a small molecule binding aptamer was dev...
RNA utilizes many different mechanisms to control gene expression. Among the regulatory elements tha...
Several techniques originating from synthetic biology have a big impact on the field of metabolic en...
SummaryRiboswitches are RNA-based genetic control elements that regulate gene expression in a ligand...
The ability to independently control the expression of multiple genes by addition of distinct small-...
Synthetic biology uses our understanding of biological systems to develop innovative solutions for c...
RNA is a versatile biomolecule capable of transferring information, taking on distinct three-dimensi...
During the last years, the important role RNA plays for regulating gene expression in all organisms ...
Riboswitches are segments of pre-mRNAs and mRNAs, present in their UTRs or introns, which are able t...
Riboswitches are common gene regulatory units mostly found in bacteria that are capable of altering ...
Riboswitches are cis-acting regulatory elements broadly distributed in bacterial mRNAs that control ...
Re-engineered riboswitches that no longer respond to cellular metabolites, but that instead can be c...
<div><p>Riboswitches are RNA-based regulators of gene expression composed of a ligand-sensing aptame...