Add to ORKGAptamers are short, single stranded nucleic acids which bind a wide range of different ligands with extraordinary high binding affinity and specificity. The steadily increasing number of aptamers is accompanied by an expanding range of applications in biotechnology. We will describe new developments in the field including the use of aptamers for conditional gene regulation and as biosensors. In addition, we will discuss the potential of aptamers as tags to visualize RNA and protein distribution in living cells and as therapeutics. Furthermore, we will consider biotechnological applications of riboswitches for gene regulation and as drug target
RNA is a versatile biomolecule capable of transferring information, taking on distinct three-dimensi...
Within the last few years, a set of synthetic riboswitches has been engineered, which expands the to...
The different functions of RNA have led to great and increasing interest in the field of synthetic b...
Aptamers are short, single stranded nucleic acids which bind a wide range of different ligands with ...
Riboswitches are common gene regulatory units mostly found in bacteria that are capable of altering ...
RNA utilizes many different mechanisms to control gene expression. Among the regulatory elements tha...
The first conditional gene expression system which employed a small molecule binding aptamer was dev...
Nucleic acid aptamers, or simply aptamers, are oligonucleotides that bind specific ligands that vary...
As the key constituents of the genetic code, the importance of nucleic acids to life has long been a...
Aptamers are single stranded ribo- or deoxyribonucleotides usually 20 to 80 nucleotides in length th...
Synthetic riboswitches are a versatile class of regulatory elements that are becoming increasingly e...
Aptamers are in vitro selected oligonucleotides capable of specific, high-affinity binding to a wide...
The utility of RNA as a sensor for in vivo enzyme evolution, metabolomics monitoring, and bacterial ...
Aptamers are short DNA or RNA oligonucleotides specialized in the specific and efficient binding to ...
Conditional gene expression systems are important tools to identify the function of essential genes ...
RNA is a versatile biomolecule capable of transferring information, taking on distinct three-dimensi...
Within the last few years, a set of synthetic riboswitches has been engineered, which expands the to...
The different functions of RNA have led to great and increasing interest in the field of synthetic b...
Aptamers are short, single stranded nucleic acids which bind a wide range of different ligands with ...
Riboswitches are common gene regulatory units mostly found in bacteria that are capable of altering ...
RNA utilizes many different mechanisms to control gene expression. Among the regulatory elements tha...
The first conditional gene expression system which employed a small molecule binding aptamer was dev...
Nucleic acid aptamers, or simply aptamers, are oligonucleotides that bind specific ligands that vary...
As the key constituents of the genetic code, the importance of nucleic acids to life has long been a...
Aptamers are single stranded ribo- or deoxyribonucleotides usually 20 to 80 nucleotides in length th...
Synthetic riboswitches are a versatile class of regulatory elements that are becoming increasingly e...
Aptamers are in vitro selected oligonucleotides capable of specific, high-affinity binding to a wide...
The utility of RNA as a sensor for in vivo enzyme evolution, metabolomics monitoring, and bacterial ...
Aptamers are short DNA or RNA oligonucleotides specialized in the specific and efficient binding to ...
Conditional gene expression systems are important tools to identify the function of essential genes ...
RNA is a versatile biomolecule capable of transferring information, taking on distinct three-dimensi...
Within the last few years, a set of synthetic riboswitches has been engineered, which expands the to...
The different functions of RNA have led to great and increasing interest in the field of synthetic b...