A heuristic in analytic number theory stipulates that sets of positive integers cannot simultaneously be additively and multiplicatively structured. The practical verification of this heuristic is the source of a great number of difficult problems, including the well-known Hardy-Littlewood tuples conjecture. Conjectures of this type are also at least morally equivalent to the expectation that a \emph{generic} multiplicative function behaves randomly on additively structured sets. \\ In this thesis, we consider several problems involving the behaviour of multiplicative functions interacting with additively structured sets. First, we prove quantitative versions of mean value theorems due to Wirsing and Hal\'{a}sz for multiplicative functions ...