Add to ORKGDuring obesity, macrophages can infiltrate metabolic tissues and contribute to chronic low-grade inflammation as well as mediate insulin resistance and diabetes. Our study addresses the essential role of macrophage JAK2, a key mediator downstream of various cytokines, hormones and growth factors, in the pathogenesis to obesity and insulin resistance. Macrophage-specific JAK2 knockout (M-JAK2M.Sc
The rising incidence of obesity and related disorders such as diabetes and heart disease has focused...
Abstract Obesity is a worldwide pandemic representing one of the major challenges that societies fac...
International audienceObesity is associated with systemic chronic low-grade inflammation, a major co...
During obesity, macrophages can infiltrate metabolic tissues and contribute to chronic low-grade inf...
The cJun NH(2)-terminal kinase (JNK) signaling pathway contributes to inflammation and plays a key r...
Obesity and the metabolic syndrome represent a serious global public health issue due to their long-...
The development of obesity, an imbalance between energy intake and energy expenditure, is associated...
SIGNIFICANCE: Obesity and diabetes are associated with chronic activation of inflammatory pathways t...
SummaryObesity-induced insulin resistance is a major factor in the etiology of type 2 diabetes, and ...
The steadily increasing obesity epidemic affects currently 30% of western populations and is causati...
It has been demonstrated in rodents and humans that chronic inflammation characterized by macrophage...
Chronic, low-grade adipose tissue inflammation is a key etiological mechanism linking the increasing...
Obesity has been described as a global epidemic and is a low-grade chronic inflammatory disease that...
Inflammation is critical for the development of obesity-associated metabolic disorders. This study a...
Inflammation is critical for the development of obesity-associated metabolic disorders. This study a...
The rising incidence of obesity and related disorders such as diabetes and heart disease has focused...
Abstract Obesity is a worldwide pandemic representing one of the major challenges that societies fac...
International audienceObesity is associated with systemic chronic low-grade inflammation, a major co...
During obesity, macrophages can infiltrate metabolic tissues and contribute to chronic low-grade inf...
The cJun NH(2)-terminal kinase (JNK) signaling pathway contributes to inflammation and plays a key r...
Obesity and the metabolic syndrome represent a serious global public health issue due to their long-...
The development of obesity, an imbalance between energy intake and energy expenditure, is associated...
SIGNIFICANCE: Obesity and diabetes are associated with chronic activation of inflammatory pathways t...
SummaryObesity-induced insulin resistance is a major factor in the etiology of type 2 diabetes, and ...
The steadily increasing obesity epidemic affects currently 30% of western populations and is causati...
It has been demonstrated in rodents and humans that chronic inflammation characterized by macrophage...
Chronic, low-grade adipose tissue inflammation is a key etiological mechanism linking the increasing...
Obesity has been described as a global epidemic and is a low-grade chronic inflammatory disease that...
Inflammation is critical for the development of obesity-associated metabolic disorders. This study a...
Inflammation is critical for the development of obesity-associated metabolic disorders. This study a...
The rising incidence of obesity and related disorders such as diabetes and heart disease has focused...
Abstract Obesity is a worldwide pandemic representing one of the major challenges that societies fac...
International audienceObesity is associated with systemic chronic low-grade inflammation, a major co...