Systemic Lupus Erythematosus (SLE) is a chronic, multisystem autoimmune disease product of the interaction between genetic and environmental factors. Although patients with pediatric-onset SLE (pSLE) and adult-onset SLE (aSLE) differ in disease presentation, activity and outcomes, all studies to date have not found any set of genes specific to pSLE as compared to aSLE. However, some studies found that early-onset SLE patients exhibited higher polygenetic risk scores. The present study included a large, multi-ethnic pSLE and aSLE cohort to identify how non-HLA and HLA genetic risk scores are associated with age of SLE onset. Samples were genotyped using Immunochip, scores were calculated based on validated SLE SNPs, analyzed in the total pop...
Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and ethnic disparitie...
Systemic lupus erythematous (SLE) is a chronic autoimmune disease associated with genetic and enviro...
Systemic Lupus Erythematosus (SLE) is one of the most relevant world-wide autoimmune disorders. The ...
Systemic Lupus Erythematosus (SLE) is a chronic, multisystem autoimmune disease product of the inter...
Background Systemic lupus erythematosus (SLE) is a chronic, multiorgan, autoimmune disease that affe...
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/94407/1/Webb_2011_Early_disease_onset.p...
Recent progress in genetics has expanded the number of the genes associated with SLE to more than 20...
Systemic lupus erythematosus (SLE) is a severe autoimmune disease with a multifactorial aetiology an...
Objectives To investigate associations between a high genetic disease risk and disease severity in p...
Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and ethnic disparitie...
Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and ethnic disparitie...
Systemic lupus erythematous (SLE) is a chronic autoimmune disease associated with genetic and enviro...
Systemic Lupus Erythematosus (SLE) is one of the most relevant world-wide autoimmune disorders. The ...
Systemic Lupus Erythematosus (SLE) is a chronic, multisystem autoimmune disease product of the inter...
Background Systemic lupus erythematosus (SLE) is a chronic, multiorgan, autoimmune disease that affe...
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/94407/1/Webb_2011_Early_disease_onset.p...
Recent progress in genetics has expanded the number of the genes associated with SLE to more than 20...
Systemic lupus erythematosus (SLE) is a severe autoimmune disease with a multifactorial aetiology an...
Objectives To investigate associations between a high genetic disease risk and disease severity in p...
Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and ethnic disparitie...
Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and ethnic disparitie...
Systemic lupus erythematous (SLE) is a chronic autoimmune disease associated with genetic and enviro...
Systemic Lupus Erythematosus (SLE) is one of the most relevant world-wide autoimmune disorders. The ...