The gut microbiome consists of trillions of microorganisms in constant interaction with the body. There is increasing evidence that these microbes have immunomodulatory effects and an important role in the pathogenesis of disease and autoimmunity. Kawasaki Disease (KD) is an inflammatory condition with a predilection for the coronary arteries. In this study, a murine model of KD using Lactobacillus casei cell wall extract (LCWE) was used to assess the effects of the microbiome in the pathogenesis of KD. We found marked changes in the microbiome between two animal facilities which correlated with disease susceptibility. Furthermore, depletion of the microbiome in susceptible mice was able to reduce disease incidence, while the transfer of ce...
Kawasaki disease (KD) is the leading cause of acquired heart disease among children. Murine and huma...
Mucus is one important component of the intestinal mucosal barrier, and loss of its functionality is...
Kawasaki disease (KD) is an acute inflammatory disorder of early childhood. It causes coronary arter...
The gut microbiome consists of trillions of microorganisms in constant interaction with the body. Th...
Alterations of gut microbiota composition and function influence the development of cardiovascular d...
[[abstract]]Although the mechanisms underlining the onset and development of Kawasaki disease (KD) r...
<p>Cardiovascular abnormalities in Kawasaki disease (KD) patients and <i>Lactobacillus casei</i> cel...
Kawasaki disease (KD) is the most common cause of acquired cardiac disease and acute vasculitis in c...
Kawasaki disease (KD) is a systemic vasculitis of unknown etiology. The innate immune system is invo...
Background: Kawasaki disease (KD) is a systemic vasculitis of unknown etiology. The innate immune sy...
Superantigens (SAgs) are implicated in the initiation of many diseases, including Kawasaki disease (...
<div><p>Background</p><p>Kawasaki disease (KD) is a systemic vasculitis of unknown etiology. The inn...
KD is an acute febrile illness and systemic vasculitis of unknown etiology among young children, whi...
Kawasaki syndrome (KS) is a necrotizing vasculitis of small- and medium-sized vessels mostly affecti...
In recent years, the gut microbiome has emerged as an im-portant player in human health.1,2 Gut micr...
Kawasaki disease (KD) is the leading cause of acquired heart disease among children. Murine and huma...
Mucus is one important component of the intestinal mucosal barrier, and loss of its functionality is...
Kawasaki disease (KD) is an acute inflammatory disorder of early childhood. It causes coronary arter...
The gut microbiome consists of trillions of microorganisms in constant interaction with the body. Th...
Alterations of gut microbiota composition and function influence the development of cardiovascular d...
[[abstract]]Although the mechanisms underlining the onset and development of Kawasaki disease (KD) r...
<p>Cardiovascular abnormalities in Kawasaki disease (KD) patients and <i>Lactobacillus casei</i> cel...
Kawasaki disease (KD) is the most common cause of acquired cardiac disease and acute vasculitis in c...
Kawasaki disease (KD) is a systemic vasculitis of unknown etiology. The innate immune system is invo...
Background: Kawasaki disease (KD) is a systemic vasculitis of unknown etiology. The innate immune sy...
Superantigens (SAgs) are implicated in the initiation of many diseases, including Kawasaki disease (...
<div><p>Background</p><p>Kawasaki disease (KD) is a systemic vasculitis of unknown etiology. The inn...
KD is an acute febrile illness and systemic vasculitis of unknown etiology among young children, whi...
Kawasaki syndrome (KS) is a necrotizing vasculitis of small- and medium-sized vessels mostly affecti...
In recent years, the gut microbiome has emerged as an im-portant player in human health.1,2 Gut micr...
Kawasaki disease (KD) is the leading cause of acquired heart disease among children. Murine and huma...
Mucus is one important component of the intestinal mucosal barrier, and loss of its functionality is...
Kawasaki disease (KD) is an acute inflammatory disorder of early childhood. It causes coronary arter...