Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer

Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity

Muthuswamy, S. K.
Siegel, P. M.
Dankort, D. L.
Webster, M. A.
Muller, W. J.

January 1994

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

HER2/Neu and the Ets transcription activator PEA3 are coordinately upregulated in human breast cancer

Benz, C. C.
O'Hagan, R. C.
Richter, B.
Scott, G. K.
Chang, C. H.
Xiong, X.
Chew, K.
Ljung, B. M.
Edgerton, S.
Thor, A.
Hassell, J. A.

January 1997

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Grb2-SH3 ligand inhibits the growth of HER2+ cancer cells and has antitumor effects in human cancer xenografts alone and in combination with docetaxel.

Gril, Brunilde
Vidal, Michel
Assayag, Franck
Poupon, Marie-France
Liu, Wang-Qing
Garbay, Christiane

July 2007

International audienceHER2 represents an important signaling pathway in breast and other cancers. He...

Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer

Dankort, D.
Maslikowski, B.
Warner, N.
Kanno, N.
Kim, H.
Wang, Z.
Moran, M. F.
Oshima, R. G.
Cardiff, R. D.
Muller, W. J.

January 2001

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

Siegel, P. M.
Ryan, E. D.
Cardiff, R. D.
Muller, W. J.

January 1999

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice

Li, B.
Rosen, J. M.
McMenamin-Balano, J.
Muller, W. J.
Perkins, A. S.

January 1997

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Accelerated mammary tumor development in mutant polyomavirus middle T transgenic mice expressing elevated levels of either the Shc or Grb2 adapter protein

Rauh, M. J.
Blackmore, V.
Andrechek, E. R.
Tortorice, C. G.
Daly, R.
Lai, V. K.
Pawson, T.
Cardiff, R. D.
Siegel, P. M.
Muller, W. J.

January 1999

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Germ-line expression of an oncogenic erbB2 allele confers resistance to erbB2-induced mammary tumorigenesis

Andrechek, E. R.
Hardy, W. R.
Laing, M. A.
Muller, W. J.

January 2004

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis

Andrechek, E. R.
Hardy, W. R.
Siegel, P. M.
Rudnicki, M. A.
Cardiff, R. D.
Muller, W. J.

January 2000

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Gene expression profiling of neu-induced mammary tumors from transgenic mice reveals genetic and morphological similarities to ErbB2-expressing human breast cancers

Andrechek, E. R.
Laing, M. A.
Girgis-Gabardo, A. A.
Siegel, P. M.
Cardiff, R. D.
Muller, W. J.

August 2003

1. The journal Cancer Research is the original source of the material.2. This article is hosted on a...

The role of Grb2 in HER2-mediates tumourigenesis

Su, Vi-Minh-Tri

January 2012

Grb2, an adaptor protein, is ubiquitously expressed and is involved in mediating a multitude of cell...

Multiple ErbB-2/Neu Phosphorylation Sites Mediate Transformation through Distinct Effector Proteins

Dankort, D.
Jeyabalan, N.
Jones, N.
Dumont, D. J.
Muller, W. J.

October 2001

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Genetic instability favoring transversions associated with ErbB2-induced mammary tumorigenesis

Liu, S.
Liu, W.
Jakubczak, J. L.
Erexson, G. L.
Tindall, K. R.
Chan, R.
Muller, W. J.
Adhya, S.
Garges, S.
Merlino, G.

January 2002

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

The Shc adaptor protein is critical for VEGF induction by Met/HGF and ErbB2 receptors and for early onset of tumor angiogenesis

Saucier, C.
Khoury, H.
Lai, K. M.
Peschard, P.
Dankort, D.
Naujokas, M. A.
Holash, J.
Yancopoulos, G. D.
Muller, W. J.
Pawson, T.
Park, M.

January 2004

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Mammalian Grb2 Regulates Multiple Steps in Embryonic Development and Malignant Transformation

Cheng, Alec M
Saxton, Tracy M
Sakai, Ryuichi
Kulkarni, Sarang
Mbamalu, Geraldine
Vogel, Wolfgang
Tortorice, Christopher G
Cardiff, Robert D
Cross, James C
Muller, William J
Pawson, Tony

December 1998

AbstractProteins with SH2 and SH3 domains link tyrosine kinases to intracellular pathways. To invest...

Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity

Muthuswamy, S. K.
Siegel, P. M.
Dankort, D. L.
Webster, M. A.
Muller, W. J.

January 1994

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

HER2/Neu and the Ets transcription activator PEA3 are coordinately upregulated in human breast cancer

Benz, C. C.
O'Hagan, R. C.
Richter, B.
Scott, G. K.
Chang, C. H.
Xiong, X.
Chew, K.
Ljung, B. M.
Edgerton, S.
Thor, A.
Hassell, J. A.

January 1997

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Grb2-SH3 ligand inhibits the growth of HER2+ cancer cells and has antitumor effects in human cancer xenografts alone and in combination with docetaxel.

Gril, Brunilde
Vidal, Michel
Assayag, Franck
Poupon, Marie-France
Liu, Wang-Qing
Garbay, Christiane

July 2007

International audienceHER2 represents an important signaling pathway in breast and other cancers. He...

Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer

Dankort, D.
Maslikowski, B.
Warner, N.
Kanno, N.
Kim, H.
Wang, Z.
Moran, M. F.
Oshima, R. G.
Cardiff, R. D.
Muller, W. J.

January 2001

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

Siegel, P. M.
Ryan, E. D.
Cardiff, R. D.
Muller, W. J.

January 1999

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice

Li, B.
Rosen, J. M.
McMenamin-Balano, J.
Muller, W. J.
Perkins, A. S.

January 1997

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Accelerated mammary tumor development in mutant polyomavirus middle T transgenic mice expressing elevated levels of either the Shc or Grb2 adapter protein

Rauh, M. J.
Blackmore, V.
Andrechek, E. R.
Tortorice, C. G.
Daly, R.
Lai, V. K.
Pawson, T.
Cardiff, R. D.
Siegel, P. M.
Muller, W. J.

January 1999

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Germ-line expression of an oncogenic erbB2 allele confers resistance to erbB2-induced mammary tumorigenesis

Andrechek, E. R.
Hardy, W. R.
Laing, M. A.
Muller, W. J.

January 2004

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis

Andrechek, E. R.
Hardy, W. R.
Siegel, P. M.
Rudnicki, M. A.
Cardiff, R. D.
Muller, W. J.

January 2000

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Gene expression profiling of neu-induced mammary tumors from transgenic mice reveals genetic and morphological similarities to ErbB2-expressing human breast cancers

Andrechek, E. R.
Laing, M. A.
Girgis-Gabardo, A. A.
Siegel, P. M.
Cardiff, R. D.
Muller, W. J.

August 2003

1. The journal Cancer Research is the original source of the material.2. This article is hosted on a...

The role of Grb2 in HER2-mediates tumourigenesis

Su, Vi-Minh-Tri

January 2012

Grb2, an adaptor protein, is ubiquitously expressed and is involved in mediating a multitude of cell...

Multiple ErbB-2/Neu Phosphorylation Sites Mediate Transformation through Distinct Effector Proteins

Dankort, D.
Jeyabalan, N.
Jones, N.
Dumont, D. J.
Muller, W. J.

October 2001

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Genetic instability favoring transversions associated with ErbB2-induced mammary tumorigenesis

Liu, S.
Liu, W.
Jakubczak, J. L.
Erexson, G. L.
Tindall, K. R.
Chan, R.
Muller, W. J.
Adhya, S.
Garges, S.
Merlino, G.

January 2002

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

The Shc adaptor protein is critical for VEGF induction by Met/HGF and ErbB2 receptors and for early onset of tumor angiogenesis

Saucier, C.
Khoury, H.
Lai, K. M.
Peschard, P.
Dankort, D.
Naujokas, M. A.
Holash, J.
Yancopoulos, G. D.
Muller, W. J.
Pawson, T.
Park, M.

January 2004

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Mammalian Grb2 Regulates Multiple Steps in Embryonic Development and Malignant Transformation

Cheng, Alec M
Saxton, Tracy M
Sakai, Ryuichi
Kulkarni, Sarang
Mbamalu, Geraldine
Vogel, Wolfgang
Tortorice, Christopher G
Cardiff, Robert D
Cross, James C
Muller, William J
Pawson, Tony

December 1998

AbstractProteins with SH2 and SH3 domains link tyrosine kinases to intracellular pathways. To invest...

Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity

Muthuswamy, S. K.
Siegel, P. M.
Dankort, D. L.
Webster, M. A.
Muller, W. J.

January 1994

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

HER2/Neu and the Ets transcription activator PEA3 are coordinately upregulated in human breast cancer

Benz, C. C.
O'Hagan, R. C.
Richter, B.
Scott, G. K.
Chang, C. H.
Xiong, X.
Chew, K.
Ljung, B. M.
Edgerton, S.
Thor, A.
Hassell, J. A.

January 1997

This article is hosted on a website external to the CBCRA Open Access Archive. Selecting “View/Open...

Grb2-SH3 ligand inhibits the growth of HER2+ cancer cells and has antitumor effects in human cancer xenografts alone and in combination with docetaxel.

Gril, Brunilde
Vidal, Michel
Assayag, Franck
Poupon, Marie-France
Liu, Wang-Qing
Garbay, Christiane

July 2007

International audienceHER2 represents an important signaling pathway in breast and other cancers. He...

Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer

Abstract

Extracted data

Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer

Abstract

Extracted data

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